Table: Solubility data for carbohydrates is compiled from experimental measurements, with
each entry accompanied by an evaluation score
assessing the reliability of the reported conditions based on five criteria: T (Temperature
Reporting), which evaluates how clearly and accurately
the temperature was reported; P (Purity of Solute), which assesses information about the chemical
purity of the solute used;
E (Equilibration Time/Agitation), which considers whether the time allowed for the solute to
dissolve and any agitation or stirring methods were reported; A (Analysis Method), which details the
method used to determine solubility (e.g., gravimetric, spectrophotometric); and A (Accuracy and/or
Precision), which gauges the reliability of the solubility measurement, including repeatability or
use of error bars.
Each criterion is rated on a five-point scale (0 - 5), where higher scores indicate more complete
and trustworthy reporting.
ID
Formula
Name
Sub Name
CAS
MW
MP
BP
Solubility (mol/L)
Solubility (g/L)
Temp (C)
Ref
Evaluation
76
C12H22O11
Lactose
4-O-B-d-Galactopyranosyl-d-glucose
Milk sugar
342.3
201.0
None
0.547
187.3
25.0
P049
1 0 1 1 1
77
C12H22O11
Lactose
4-O-B-d-Galactopyranosyl-d-glucose
Milk sugar
342.3
201.0
None
0.6
205.4
30.0
D011
1 0 1 0 1
78
C12H22O11
Lactose
4-O-B-d-Galactopyranosyl-d-glucose
Milk sugar
342.3
201.0
None
0.588
201.3
30.0
M043
1 0 0 0 2
79
C12H22O11
Lactose
4-O-B-d-Galactopyranosyl-d-glucose
Milk sugar
342.3
201.0
None
0.5843
200.0
40.0
C401
1 0 0 0 0
80
C12H22O11
Lactose
4-O-B-d-Galactopyranosyl-d-glucose
Milk sugar
342.3
201.0
None
0.7298
249.8
40.0
M043
1 0 0 0 2
81
C12H22O11
Lactose
4-O-B-d-Galactopyranosyl-d-glucose
Milk sugar
342.3
201.0
None
0.7574
259.3
60.0
C401
1 0 0 0 0
82
C12H22O11
Lactose
4-O-B-d-Galactopyranosyl-d-glucose
Milk sugar
342.3
201.0
None
1.067
365.1
60.0
M043
1 0 0 0 2
83
C12H22O11
Lactose
4-O-B-d-Galactopyranosyl-d-glucose
Milk sugar
342.3
201.0
None
0.9738
333.3
80.0
C401
1 0 0 0 0
84
C12H22O11
Lactose
4-O-B-d-Galactopyranosyl-d-glucose
Milk sugar
342.3
201.0
None
1.475
505.0
80.0
M043
1 0 0 0 2
85
C12H22O11
Lactose
4-O-B-d-Galactopyranosyl-d-glucose
Milk sugar
342.3
201.0
None
1.699
581.6
89.0
D041
1 0 0 0 2
86
C12H22O11
Lactose
4-O-B-d-Galactopyranosyl-d-glucose
Milk sugar
342.3
201.0
None
1.096
375.0
95.0
C401
1 0 0 0 0
87
C12H22O11
Lactose
4-O-B-d-Galactopyranosyl-d-glucose
Milk sugar
342.3
201.0
None
1.124
384.6
100.0
C401
1 0 0 0 0
88
C12H22O11
Lactose
4-O-B-d-Galactopyranosyl-d-glucose
Milk sugar
342.3
201.0
None
1.767
604.7
100.0
M043
1 0 0 0 2
89
C12H22O11
Lactose
4-O-B-d-Galactopyranosyl-d-glucose
Milk sugar
342.3
201.0
None
0.4775
163.5
rt
D021
0 0 1 1 2
90
C12H22O11
Sucrose
Saccharose
β-d-Fructofuranosyl-α-d-glucopyranoside
342.3
191.0
None
1.14
390.2
0.0
C401
1 0 0 0 0
91
C12H22O11
Sucrose
Saccharose
β-d-Fructofuranosyl-α-d-glucopyranoside
342.3
191.0
None
1.878
642.9
0.0
D041
1 0 0 0 2
92
C12H22O11
Sucrose
Saccharose
β-d-Fructofuranosyl-α-d-glucopyranoside
342.3
191.0
None
1.876
642.1
0.0
G046
1 0 1 1 2
93
C12H22O11
Sucrose
Saccharose
β-d-Fructofuranosyl-α-d-glucopyranoside
342.3
191.0
None
1.142
390.9
0.0
H094
1 0 0 0 2
94
C12H22O11
Sucrose
Saccharose
β-d-Fructofuranosyl-α-d-glucopyranoside
342.3
191.0
None
1.874
641.6
0.0
M043
1 0 0 0 2
95
C12H22O11
Sucrose
Saccharose
β-d-Fructofuranosyl-α-d-glucopyranoside
342.3
191.0
None
1.884
645.0
0.0
P052
1 0 2 2 2
96
C12H22O11
Sucrose
Saccharose
β-d-Fructofuranosyl-α-d-glucopyranoside
342.3
191.0
None
1.88
643.5
0.9
M074
1 0 0 0 2
97
C12H22O11
Sucrose
Saccharose
β-d-Fructofuranosyl-α-d-glucopyranoside
342.3
191.0
None
1.157
396.1
10.0
H094
1 0 0 0 2
98
C12H22O11
Sucrose
Saccharose
β-d-Fructofuranosyl-α-d-glucopyranoside
342.3
191.0
None
1.914
655.2
10.0
M043
1 0 0 0 2
99
C12H22O11
Sucrose
Saccharose
β-d-Fructofuranosyl-α-d-glucopyranoside
342.3
191.0
None
1.943
665.0
12.5
F300
1 0 0 0 2
100
C12H22O11
Sucrose
Saccharose
β-d-Fructofuranosyl-α-d-glucopyranoside
342.3
191.0
None
1.938
663.3
15.0
D041
1 0 0 0 2
* The data is collected from "HANDBOOK OF AQUEOUS SOLUBILITY DATA" by Samuel H.
Yalkowsky, Yan He, and Parijat Jain. The book is published by Taylor and Francis Group, LLC.
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Abbreviations
1. amb: ambient temperature
2. c: cold water
3. h: hot water
4. rt: room temperature
5. ns: temperature not stated
6. EFG: stimated from graph
7. LCST: lower critical solution temperature
8. UCST: upper critical solution temperature