Table: Solubility data for carbohydrates is compiled from experimental measurements, with
each entry accompanied by an evaluation score
assessing the reliability of the reported conditions based on five criteria: T (Temperature
Reporting), which evaluates how clearly and accurately
the temperature was reported; P (Purity of Solute), which assesses information about the chemical
purity of the solute used;
E (Equilibration Time/Agitation), which considers whether the time allowed for the solute to
dissolve and any agitation or stirring methods were reported; A (Analysis Method), which details the
method used to determine solubility (e.g., gravimetric, spectrophotometric); and A (Accuracy and/or
Precision), which gauges the reliability of the solubility measurement, including repeatability or
use of error bars.
Each criterion is rated on a five-point scale (0 - 5), where higher scores indicate more complete
and trustworthy reporting.
ID
Formula
Name
Sub Name
CAS
MW
MP
BP
Solubility (mol/L)
Solubility (g/L)
Temp (C)
Ref
Evaluation
26
C6H12O6
Fructose
d-Fructose
d-(–)-Fructose
180.16
129.0
None
2.629
473.7
60.0
M043
1 0 0 0 1
27
C6H12O6
Fructose
d-Fructose
d-(–)-Fructose
180.16
129.0
None
4.709
848.4
70.0
A420
0 0 0 0 0
28
C6H12O6
d-Galactose
Galactose
(+)-Galactose
180.16
169.0
None
0.5046
90.91
0.0
D041
1 0 0 0 1
29
C6H12O6
d-Galactose
Galactose
(+)-Galactose
180.16
169.0
None
2.247
404.8
25.0
D041
1 0 0 0 1
30
C6H12O6
d-Galactose
Galactose
(+)-Galactose
180.16
169.0
None
2.253
405.8
rt
D021
0 0 1 1 2
31
C6H12O6
α-Glucose
α-d-Glucose
d-α-Glucose
180.16
154.5
None
1.355
244.1
0.0
D041
1 0 0 0 2
32
C6H12O6
α-Glucose
α-d-Glucose
d-α-Glucose
180.16
154.5
None
2.019
363.8
10.0
Y020
1 1 2 1 2
33
C6H12O6
α-Glucose
α-d-Glucose
d-α-Glucose
180.16
154.5
None
2.775
500.0
20.0
F300
1 0 0 0 0
34
C6H12O6
α-Glucose
α-d-Glucose
d-α-Glucose
180.16
154.5
None
2.096
377.5
20.0
Y020
1 1 2 1 2
35
C6H12O6
α-Glucose
α-d-Glucose
d-α-Glucose
180.16
154.5
None
2.501
450.5
25.0
D041
1 0 0 0 2
36
C6H12O6
α-Glucose
α-d-Glucose
d-α-Glucose
180.16
154.5
None
2.17
390.9
30.0
Y020
1 1 2 1 2
37
C6H12O6
α-Glucose
α-d-Glucose
d-α-Glucose
180.16
154.5
None
2.242
404.0
40.0
Y020
1 1 2 1 2
38
C6H12O6
α-Glucose
α-d-Glucose
d-α-Glucose
180.16
154.5
None
2.313
416.8
50.0
Y020
1 1 2 1 2
39
C6H12O6
α-Glucose
α-d-Glucose
d-α-Glucose
180.16
154.5
None
2.346
422.7
54.7
Y020
1 1 2 1 2
40
C6H12O6
α-Glucose
α-d-Glucose
d-α-Glucose
180.16
154.5
None
1.942
349.8
0.0
Y020
1 1 2 1 2
41
C6H12O6
Glucose (monohydrate)
RN:
50-99-7
198.17
83.0
None
1.449
287.1
10.0
Y020
1 1 2 1 2
42
C6H12O6
Glucose (monohydrate)
RN:
50-99-7
198.17
83.0
None
1.619
320.9
20.0
Y020
1 1 2 1 2
43
C6H12O6
Glucose (monohydrate)
RN:
50-99-7
198.17
83.0
None
1.781
353.0
30.0
Y020
1 1 2 1 2
44
C6H12O6
Glucose (monohydrate)
RN:
50-99-7
198.17
83.0
None
1.933
383.1
40.0
Y020
1 1 2 1 2
45
C6H12O6
Glucose (monohydrate)
RN:
50-99-7
198.17
83.0
None
2.072
410.6
50.0
Y020
1 1 2 1 2
46
C6H12O6
Glucose (monohydrate)
RN:
50-99-7
198.17
83.0
None
1.784
353.6
73.2
Y020
1 1 2 1 2
47
C6H12O6
Glucose (monohydrate)
RN:
50-99-7
198.17
83.0
None
1.274
252.5
0.0
Y020
1 1 2 1 2
48
C12H18N2O5
d-Mannosephenylhydrazone
d-Mannose-phenylhydrazon
RN:
270.29
195.5
None
0.03811
10.3
100.0
F300
1 0 0 0 2
49
C12H22O11
Maltose
d-Glucose, 4-O-α-d-glucopyranosyl-
α-Maltose
342.3
102.5
None
0.7166
245.3
0.0
C401
1 0 0 0 0
50
C12H22O11
Maltose
d-Glucose, 4-O-α-d-glucopyranosyl-
α-Maltose
342.3
102.5
None
1.061
363.1
0.0
M043
1 0 0 0 1
* The data is collected from "HANDBOOK OF AQUEOUS SOLUBILITY DATA" by Samuel H.
Yalkowsky, Yan He, and Parijat Jain. The book is published by Taylor and Francis Group, LLC.
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Abbreviations
1. amb: ambient temperature
2. c: cold water
3. h: hot water
4. rt: room temperature
5. ns: temperature not stated
6. EFG: stimated from graph
7. LCST: lower critical solution temperature
8. UCST: upper critical solution temperature