Aqueous Solubility of Carbohydrates

Table: Solubility data for carbohydrates is compiled from experimental measurements, with each entry accompanied by an evaluation score assessing the reliability of the reported conditions based on five criteria: T (Temperature Reporting), which evaluates how clearly and accurately the temperature was reported; P (Purity of Solute), which assesses information about the chemical purity of the solute used; E (Equilibration Time/Agitation), which considers whether the time allowed for the solute to dissolve and any agitation or stirring methods were reported; A (Analysis Method), which details the method used to determine solubility (e.g., gravimetric, spectrophotometric); and A (Accuracy and/or Precision), which gauges the reliability of the solubility measurement, including repeatability or use of error bars. Each criterion is rated on a five-point scale (0 - 5), where higher scores indicate more complete and trustworthy reporting.

ID Formula Name Sub Name CAS MW MP BP Solubility (mol/L) Solubility (g/L) Temp (C) Ref Evaluation
126 C18H30O15 Triamylose (tetrahydrate) RN: MP (°C): 558.49 MW: None 0.02298 12.83 20.0 P048 1 2 1 1 1


* The data is collected from "HANDBOOK OF AQUEOUS SOLUBILITY DATA" by Samuel H. Yalkowsky, Yan He, and Parijat Jain. The book is published by Taylor and Francis Group, LLC.


References

G317. Gabas, N., T. Carillon, and N. Hiquily, Solubilities of d-xylose and d -mannose in water–ethanol mix- tures at 25°C, Journal of Chemical and Engineering Data, 33, 128–130, 1988.

F300. Freier, R.K., Aqueous Solutions Volume 1: Data for Inorganic and Organic Compounds, Walter de Gruyter, New York, 1, 1976.

D041. Dawson, R.M.C., D.C. Elliott, W.H. Elliott, and K.M. Jones, Data for Biochemical Research, 1, 1, Oxford University Press, Pergamon, 1969.

J019. Jackson, R.F. and C.G. Silsbee, The Solubility of Dextrose in Water, Scientifc Papers, National Bureau of Standards, 17, 715–724, 1922.

M043. Mullin, J.W., Crystallisation, Butterworths, London, 425–426, 1972.

Y020. Young, F.E., d-Glucose–water phase diagram, Journal of Physical Chemistry, 61, 616–619, 1957.

K122. Kelly, F.H.C., Phase equilibria in sugar solutions. II. Ternary systems of water–sucrose–hexose, Journal of Applied Chemistry, 4, 405–406, 1954.

M137. Mistry, F.R. and S.M. Barnett, An equilibrium phase diagram for the glucose-cellobiose-water system at 30.5°C, Journal of Chemical and Engineering Data, 25, 223–226, 1980.

B354. Bockstanz, G.L., M. Buffa, and C.T. Lira, Solubilities of alpha-anhydrous glucose in ethanol/water mix- tures, Journal of Chemical and Engineering Data, 34, 426–429, 1989.

K135. Kelly, F.H.C., Phase equilibria in sugar solutions. III. Ternary systems of water–hexose–inorganic salt, Journal of Applied Chemistry, 4, 407–408, 1954.

K136. Kelly, F.H.C., Phase equilibria in sugar solutions. IV. Ternary system of water–glucose–fructose, Journal of Applied Chemistry, 4, 409–411, 1954.

A420. Abed, Y., N. Gabas, M.L. Delia, and T. Bounahmidi, Measurement of liquid–solid phase equilibrium in ternary systems of water–sucrose–glouse and water–sucrose–fructose, and predictions with UNIFAC, Fluid Phase Equilibria, 73, 175–184, 1992.

D021. Dehn, W.M., Comparative solubilities in water, in pyridine and in aqueous pyridine, Journal of the American Chemical Society, 39, 1399–1404, 1917.

C401. Cakebread, S.H., Confectionery ingredients—composition and properties, Confectionery Productions, 274–278, 1971.

P052. Peter, P.N., Solubility relationships of lactose-sucrose solutions. I. Lactose-sucrose solubilities at low temperatures, Journal of Physical Chemistry, 32, 1856–1864, 1928.

P049. Pucher, G. and W.M. Dehn, Solubilities in mixtures of two solvents, Journal of the American Chemical Society, 43, 1753–1758, 1921.

D011. DeLuca, P.P. and L. Lachman, Lyophilization of pharmaceuticals. I. Effect of certain physical–chemical properties, Journal of Pharmaceutical Sciences, 54, 617–624, 1965.

G046. Grube, V.G. and M. Nubaum, Phasentheoretische untersuchungen uber die entzuckerung der melasse, Zeitschrift fuer Elektrochemie, 34, 91–98, 1928.

H094. Horiba, S., Sucrose–water, Memoirs of the College of Engineering, Kyoto Imperial University, 2, 519– 519, 1917.

M074. Mondain-Monval, P., Sur la solubilite du saccharose, Comptes Rendus Hebdomadaires des Seances de l’Academie des Sciences, 181, 37–40, 1925.

W013. Wise, W.S. and E.B. Nicholson, The solubilities and heats of crystallisation of sucrose and methyl alpha- d-glucoside in aqueous solution, Journal of the Chemical Society (London), 2714–2716, 1955.

G060. Grut, D., The solubility of sucrose, Zeitschrift fuer die Zuckerindustrie Czcchoslov, 61, 345, 1937. G061 Glew, D.N. and E.A. Moelwyn-Hughes, Chemical statics of the methyl halides in water, Discussions of the Faraday Society, 15, 150–161, 1953.

R427. Raevsky, O.A., O.E. Raevskaja, and K.-J. Schaper, Analysis of Water Solubility Data on the Basis of HYBOT Descriptors. Part 3. Solubility of solid neutral chemicals and drugs, QSAR & Combinatorial Science, 23, 327–343, 2004.

P048. Pringsheim, H. and D. Dernikos, Weiteres uber die polyamylosen. (Beitrage zur chemie der starke, VI.), Berichte der Deutschen Chemischen Gesellschaft, 55, 1433–1449, 1922.

Abbreviations

1. amb: ambient temperature
2. c: cold water
3. h: hot water
4. rt: room temperature
5. ns: temperature not stated
6. EFG: stimated from graph
7. LCST: lower critical solution temperature
8. UCST: upper critical solution temperature