Aqueous Solubility of Carbohydrates

Table: Solubility data for carbohydrates is compiled from experimental measurements, with each entry accompanied by an evaluation score assessing the reliability of the reported conditions based on five criteria: T (Temperature Reporting), which evaluates how clearly and accurately the temperature was reported; P (Purity of Solute), which assesses information about the chemical purity of the solute used; E (Equilibration Time/Agitation), which considers whether the time allowed for the solute to dissolve and any agitation or stirring methods were reported; A (Analysis Method), which details the method used to determine solubility (e.g., gravimetric, spectrophotometric); and A (Accuracy and/or Precision), which gauges the reliability of the solubility measurement, including repeatability or use of error bars. Each criterion is rated on a five-point scale (0 - 5), where higher scores indicate more complete and trustworthy reporting.

ID Formula Name Sub Name CAS MW MP BP Solubility (mol/L) Solubility (g/L) Temp (C) Ref Evaluation
1 C5H10O5 d-Xylose α-Xylose Wood sugar 150.13 144.5 None 2.879 432.2 25.0 G317 0 0 0 0 0
2 C5H10O5 l-Arabinose l-Arabinopyranose RN: 150.13 158.0 None 2.482 372.6 10.0 F300 1 0 0 0 2
3 C6H12O6 d-Mannose d-(+)-Mannose Seminose 180.16 132.0 None 3.956 712.6 17.0 D041 1 0 0 0 2
4 C6H12O6 d-Mannose d-(+)-Mannose Seminose 180.16 132.0 None 3.957 712.8 17.0 F300 1 0 0 0 2
5 C6H12O6 d-Mannose d-(+)-Mannose Seminose 180.16 132.0 None 2.399 432.2 25.0 G317 0 0 0 0 0
6 C6H12O6 Glucose d-Glucose d(+)-Glucose 180.16 146.0 None 1.954 352.0 0.5 J019 1 0 1 2 2
7 C6H12O6 Glucose d-Glucose d(+)-Glucose 180.16 146.0 None 1.749 315.1 0.0 M043 1 0 0 0 1
8 C6H12O6 Glucose d-Glucose d(+)-Glucose 180.16 146.0 None 2.286 411.8 10.0 M043 1 0 0 0 1
9 C6H12O6 Glucose d-Glucose d(+)-Glucose 180.16 146.0 None 2.271 409.1 10.0 Y020 1 1 2 1 2
10 C6H12O6 Glucose d-Glucose d(+)-Glucose 180.16 146.0 None 3.365 606.3 15.0 D041 1 0 0 0 2
11 C6H12O6 Glucose d-Glucose d(+)-Glucose 180.16 146.0 None 2.66 479.2 20.0 M043 1 0 0 0 1
12 C6H12O6 Glucose d-Glucose d(+)-Glucose 180.16 146.0 None 2.314 416.8 20.0 Y020 1 1 2 1 2
13 C6H12O6 Glucose d-Glucose d(+)-Glucose 180.16 146.0 None 3.033 546.4 30.0 J019 1 0 1 2 2
14 C6H12O6 Glucose d-Glucose d(+)-Glucose 180.16 146.0 None 3.031 546.0 30.0 K122 1 1 1 1 2
15 C6H12O6 Glucose d-Glucose d(+)-Glucose 180.16 146.0 None 3.028 545.5 30.0 M043 1 0 0 0 2
16 C6H12O6 Glucose d-Glucose d(+)-Glucose 180.16 146.0 None 2.355 424.4 30.0 Y020 1 1 2 1 2
17 C6H12O6 Glucose d-Glucose d(+)-Glucose 180.16 146.0 None 1.901 342.5 30.5 M137 2 1 2 2 2
18 C6H12O6 Glucose d-Glucose d(+)-Glucose 180.16 146.0 None 2.042 367.8 35.0 B354 0 0 0 0 0
19 C6H12O6 Fructose d-Fructose d-(–)-Fructose 180.16 129.0 None 2.379 428.6 0.0 M043 1 0 0 0 1
20 C6H12O6 Fructose d-Fructose d-(–)-Fructose 180.16 129.0 None 4.318 778.0 20.0 F300 1 0 0 0 2
21 C6H12O6 Fructose d-Fructose d-(–)-Fructose 180.16 129.0 None 2.467 444.4 20.0 M043 1 0 0 0 1
22 C6H12O6 Fructose d-Fructose d-(–)-Fructose 180.16 129.0 None 4.524 815.0 30.0 K122 1 1 1 1 2
23 C6H12O6 Fructose d-Fructose d-(–)-Fructose 180.16 129.0 None 4.524 815.0 30.0 K135 1 1 1 1 2
24 C6H12O6 Fructose d-Fructose d-(–)-Fructose 180.16 129.0 None 24.48 4410.0 30.0 K136 1 1 1 1 2
25 C6H12O6 Fructose d-Fructose d-(–)-Fructose 180.16 129.0 None 2.55 459.5 40.0 M043 1 0 0 0 1


* The data is collected from "HANDBOOK OF AQUEOUS SOLUBILITY DATA" by Samuel H. Yalkowsky, Yan He, and Parijat Jain. The book is published by Taylor and Francis Group, LLC.


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Abbreviations

1. amb: ambient temperature
2. c: cold water
3. h: hot water
4. rt: room temperature
5. ns: temperature not stated
6. EFG: stimated from graph
7. LCST: lower critical solution temperature
8. UCST: upper critical solution temperature