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Glycomaterials Chronicles

Explore curated research chronicles, originating experimental data, spectral analysis, and related open-access publications across carbohydrate materials research.

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In-House Research
<p>TREM2 on microglia cell surface binds to and forms functional binary complexes with heparan sulfate modified with 6-O-sulfation and iduronic acid</p>

TREM2 on microglia cell surface binds to and forms functional binary complexes with heparan sulfate modified with 6-O-sulfation and iduronic acid

Ilayda Ozsan McMillan, Li Liang, Guowei Su, Xuehong Song, Kelly Drago, Hua Yang,...

Division of Chemical Biology and Medicinal Chemistry, University of North Caroli...
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In-House Research
<p>Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin</p>

Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin

J. Yang; Y. Song; W. Jin; K. Xia; G. C. Burnett; W. Qiao; J. T. Bates; V. H. Pom...

1The Key Laboratory of Molecular Microbiology and Technology, Ministry of Educat...
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In-House Research
<p>Inhibition of sulfated glycans on the binding of dengue virus envelope protein to heparin</p>

Inhibition of sulfated glycans on the binding of dengue virus envelope protein to heparin

Jiyuan Yang, Payel Datta, Ke Xia, Vitor H. Pomin, Chunyu Wang, Mingqiang Qiao, R...

Departments of Chemical and Biological Engineering, Rensselaer Polytechnic Insti...
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External User
<p>Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation</p>

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

Daniel Wrapp, Nianshuang Wang, Kizzmekia S. Corbett, Jory A. Goldsmith, Ching-Li...

Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602, U...
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In-House Research
<p>Applications of Surface Plasmon Resonance in Heparan Sulfate Interactome Research</p>

Applications of Surface Plasmon Resonance in Heparan Sulfate Interactome Research

Payel Datta, Jonathan S. Dordick, Fuming Zhang

Department of Chemical and Biological Engineering, Center for Biotechnology and ...
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In-House Research
<p>Marine-derived sulfated glycans display a potent virostatic mechanism to block herpes simplex virus type-1 (HSV-1) entry and spread</p>

Marine-derived sulfated glycans display a potent virostatic mechanism to block herpes simplex virus type-1 (HSV-1) entry and spread

James Elste, Michele Rabbitt, Chunyu Wang, Jonathan S. Dordick, Vaibhav Tiwari, ...

Department of Microbiology & Immunology, College of Graduate Studies, Midwestern...
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In-House Research
<p>Characterization of heparin interactions with Clostridioides difficile toxins and its potential as anti-CDI therapeutics</p>

Characterization of heparin interactions with Clostridioides difficile toxins and its potential as anti-CDI therapeutics

Fuming Zhang, Shaohui Wang, Jiyuan Yang, Keith Fraser, James M. Gibson, Chunyu W...

Department of Chemical and Biological Engineering, Center for Biotechnology and ...
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In-House Research
<p>Structural Characteristics of Heparin Binding to SARS-CoV-2 Spike Protein RBD of Omicron Sub-Lineages BA.2.12.1, BA.4 and BA.5</p>

Structural Characteristics of Heparin Binding to SARS-CoV-2 Spike Protein RBD of Omicron Sub-Lineages BA.2.12.1, BA.4 and BA.5

Deling Shi1,2, Changkai Bu1, Peng He2, Yuefan Song2, Jonathan S. Dordick2, Rober...

1National Glycoengineering Research Center, Shandong University, Qingdao 266237,...
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In-House Research
<p>Interactions of marine sulfated glycans with antithrombin and platelet factor 4</p>

Interactions of marine sulfated glycans with antithrombin and platelet factor 4

Wenjing Zhang, Weihua Jin, Vitor Hugo Pomin, Fuming Zhang, Robert J. Linhardt

1Department of Endocrinology, Sir Run Run Shaw Hospital, Zhejiang University Sch...
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In-House Research
<p>Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants</p>

Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants

Gelbach, Adrianne L., Fuming Zhang, Seok-Joon Kwon, John T. Bates, Andrew P. Far...

1Department of Biological Sciences, Center for Biotechnology and Interdisciplina...
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In-House Research
<p>Fractionation of sulfated galactan from the red alga&nbsp;<em>Botryocladia occidentalis</em>&nbsp;separates its anticoagulant and anti-SARS-CoV-2 properties</p>

Fractionation of sulfated galactan from the red alga Botryocladia occidentalis separates its anticoagulant and anti-SARS-CoV-2 properties

Seon Beom Kim 1, Mary Zoepfl 2, Priyanka Samanta 1, Fuming Zhang 3, Ke Xia 3, Re...
  1. Department of BioMolecular Sciences, University of Mississippi, University, M...
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In-House Research
<p>Enzymatic synthesis of low molecular weight heparins from&nbsp;<em>N</em>-sulfo heparosan depolymerized by heparanase or heparin lyase</p>

Enzymatic synthesis of low molecular weight heparins from N-sulfo heparosan depolymerized by heparanase or heparin lyase

Yanlei Yu a, Li Fu b e, Peng He b, Ke Xia b, Sony Varghese e, Jonathan Dordick c...

College of Pharmaceutical Science & Collaborative Innovation Center for Yangtze ...
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In-House Research
<p>Cholesterol Chip for the Study of Cholesterol&ndash;Protein Interactions Using SPR</p>

Cholesterol Chip for the Study of Cholesterol–Protein Interactions Using SPR

Peng He1,2,†, Shannon Faris1,2,†, Reddy Sudheer Sagabala3, Payel Datta1,2, Zihan...
  1. Department of Chemistry and Chemical Biology, Rensselaer Polytechnic Institut...
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In-House Research
<p>Anti-SARS-CoV-2 and anticoagulant properties of&nbsp;<em>Pentacta pygmaea</em>&nbsp;fucosylated chondroitin sulfate depend on high molecular weight structures</p>

Anti-SARS-CoV-2 and anticoagulant properties of Pentacta pygmaea fucosylated chondroitin sulfate depend on high molecular weight structures

Rohini Dwivedi, Poonam Sharma, Friederike Eilts, Fuming Zhang, Robert J Linhardt...

Department of BioMolecular Sciences, University of Mississippi, Oxford, Mississi...
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In-House Research
<p>Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection</p>

Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection

Rohini Dwivedi 1, Priyanka Samanta 1, Poonam Sharma 2, Fuming Zhang 3, Sushil K....
  1. Department of BioMolecular Sciences, University of Mississippi, Oxford, Missi...
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In-House Research
<p>Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate</p>

Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate

Fuming Zhang1,*, Peng He2, Andre L. Rodrigues1, Walter Jeske3, Ritesh Tandon4,5,...
  1. Department of Chemical and Biological Engineering, Center for Biotechnology a...
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In-House Research
<p>Marine sulfated glycans inhibit the interaction of heparin with S-protein of SARS-CoV-2 Omicron XBB variant</p>

Marine sulfated glycans inhibit the interaction of heparin with S-protein of SARS-CoV-2 Omicron XBB variant

Peng He1,2 · Yuefan Song1,3 · Weihua Jin1,4 · Yunran Li1,3 · Ke Xia1,3 · Seon Be...

1 Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic...
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In-House Research
<p>Anti-SARS-CoV-2 Activity of Rhamnan Sulfate from&nbsp;Monostroma nitidum</p>

Anti-SARS-CoV-2 Activity of Rhamnan Sulfate from Monostroma nitidum

Song, Yuefan, Peng He, Andre L. Rodrigues, Payel Datta, Ritesh Tandon, John T. B...

Departments of Chemistry and Chemical Biology, Center for Biotechnology and Inte...
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In-House Research
<p>Kinetic and Structural Aspects of Glycosaminoglycan&ndash;Monkeypox Virus Protein A29 Interactions Using Surface Plasmon Resonance</p>

Kinetic and Structural Aspects of Glycosaminoglycan–Monkeypox Virus Protein A29 Interactions Using Surface Plasmon Resonance

Deling Shi1,2,Peng He2, Yuefan Song2, Shuihong Cheng2, Robert J. Linhardt2, Jona...

1National Glycoengineering Research Center, Shandong University, Qingdao 266237,...
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In-House Research
<p>SPR Sensor-Based Analysis of the Inhibition of Marine Sulfated Glycans on Interactions between Monkeypox Virus Proteins and Glycosaminoglycans</p>

SPR Sensor-Based Analysis of the Inhibition of Marine Sulfated Glycans on Interactions between Monkeypox Virus Proteins and Glycosaminoglycans

Peng He1,2, Deling Shi1,2, Yunran Li1,3, Ke Xia1,2, Seon Beom Kim4,5, Rohini Dwi...

1Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic ...
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