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Glycomaterials Chronicles

Explore curated research chronicles, originating experimental data, spectral analysis, and related open-access publications across carbohydrate materials research.

Open Access publications hosted on VTechWorks
In-House Research
<p>Toward Automatic Inference of Glycan Linkages Using MSn and Machine Learning - Proof of Concept Using Sialic Acid Linkages</p>

Toward Automatic Inference of Glycan Linkages Using MSn and Machine Learning - Proof of Concept Using Sialic Acid Linkages

Xinyi Ni, Nathan B. Murray, Stephanie Archer-Hartmann, Lauren E. Pepi, Richard F...

  1. Brandeis University
  2. University of Georgia, Athens
  3. Virginia Tech
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In-House Research
<p>TREM2 on microglia cell surface binds to and forms functional binary complexes with heparan sulfate modified with 6-O-sulfation and iduronic acid</p>

TREM2 on microglia cell surface binds to and forms functional binary complexes with heparan sulfate modified with 6-O-sulfation and iduronic acid

Ilayda Ozsan McMillan, Li Liang, Guowei Su, Xuehong Song, Kelly Drago, Hua Yang,...

Division of Chemical Biology and Medicinal Chemistry, University of North Caroli...

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External User
<p>Discovery of a single-subunit oligosaccharyltransferase that enables glycosylation of full-length IgG antibodies in bacteria</p>

Discovery of a single-subunit oligosaccharyltransferase that enables glycosylation of full-length IgG antibodies in bacteria

Belen Sotomayor, Thomas C. Donahue, Sai Pooja Mahajan, May N. Taw, Sophia W. Hul...

Department of Chemical and Biomolecular Engineering, Johns Hopkins University, B...

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In-House Research
<p>Fibrolamellar Carcinomas&ndash;Growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides</p>

Fibrolamellar Carcinomas–Growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides

Wencheng Zhang a b c d 1, Yongmei Xu e f 1 2, Xicheng Wang b c d 3, Tsunekazu Oi...

aDepartment of Cell Biology and Physiology, University of North Carolina, Chapel...

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In-House Research
<p>New insights into the binding of PF4 to long heparin oligosaccharides in ultralarge complexes using mass spectrometry</p>

New insights into the binding of PF4 to long heparin oligosaccharides in ultralarge complexes using mass spectrometry

Deling Shi 1 2, Huimin Zhao 1, Changkai Bu 1, Keith Fraser 2 3, Haoran Wang 1, J...

1National Glycoengineering Research Center, Shandong University, Qingdao, Shando...

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In-House Research
<p>Seaweed-derived fucoidans and rhamnan sulfates serve as potent anti-SARS-CoV-2 agents with potential for prophylaxis</p>

Seaweed-derived fucoidans and rhamnan sulfates serve as potent anti-SARS-CoV-2 agents with potential for prophylaxis

Yuefan Song a, Amit Singh b, Maisha M. Feroz a c, Shirley Xu a c, Fuming Zhang a...

a Center for Biotechnology & Interdisciplinary Studies, Rensselaer Polytechnic I...

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In-House Research
<p>Sulfated fuco-manno-glucuronogalactan alleviates pancreatic beta cell senescence via PI3K/AKT/FoxO1 pathway</p>

Sulfated fuco-manno-glucuronogalactan alleviates pancreatic beta cell senescence via PI3K/AKT/FoxO1 pathway

Wenjing Zhang a 1, Nan Wu a 1, Hong Wang a, Genxiang Mao c, Xiaojun Yan d, Fumin...

aDepartment of Endocrinology and Metabolism, Sir Run Run Shaw Hospital, Zhejiang...

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In-House Research
<p>Developing a solid-phase method for the enzymatic synthesis of heparan sulfate and chondroitin sulfate backbones</p>

Developing a solid-phase method for the enzymatic synthesis of heparan sulfate and chondroitin sulfate backbones

Stancanelli, Eduardo; Liu, Wei; Su, Guowei; Padagala, Vijay; Liu, Jian

  • 1Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pha...
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External User
<p>Systematic Evaluation of Macromolecular Carbohydrate-LectinRecognition Using Precision Glycopolymers</p>

Systematic Evaluation of Macromolecular Carbohydrate-LectinRecognition Using Precision Glycopolymers

Cole A. Williams*, Daniel J. Stone*, Soumil Y. Joshi, Gokhan Yilmaz, Parisa Farz...

Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712,...

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In-House Research
<p>Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin</p>

Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin

J. Yang; Y. Song; W. Jin; K. Xia; G. C. Burnett; W. Qiao; J. T. Bates; V. H. Pom...

1The Key Laboratory of Molecular Microbiology and Technology, Ministry of Educat...

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In-House Research
<p>Inhibition of sulfated glycans on the binding of dengue virus envelope protein to heparin</p>

Inhibition of sulfated glycans on the binding of dengue virus envelope protein to heparin

Jiyuan Yang, Payel Datta, Ke Xia, Vitor H. Pomin, Chunyu Wang, Mingqiang Qiao, R...

Departments of Chemical and Biological Engineering, Rensselaer Polytechnic Insti...

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In-House Research
<p>Chemoenzymatic synthesis of sulfur-linked sugar polymers as heparanase inhibitors</p>

Chemoenzymatic synthesis of sulfur-linked sugar polymers as heparanase inhibitors

Peng He, Xing Zhang, Ke Xia, Dixy E. Green, Sultan Baytas, Yongmei Xu, Truong Ph...

Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic I...

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In-House Research
<p>The diverse role of heparan sulfate and other GAGs in SARS-CoV-2 infections and therapeutics</p>

The diverse role of heparan sulfate and other GAGs in SARS-CoV-2 infections and therapeutics

Friederike Eilts a b 1, Sarah Bauer a 1, Keith Fraser c 1, Jonathan S. Dordick a...

aDepartment of Chemical and Biological Engineering, Center for Biotechnology and...

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In-House Research
<p>Soluble &alpha;-klotho and heparin modulate the pathologic cardiac actions of fibroblast growth factor 23 in chronic kidney disease</p>

Soluble α-klotho and heparin modulate the pathologic cardiac actions of fibroblast growth factor 23 in chronic kidney disease

Christopher Yanucil 1, Dominik Kentrup 1 2, Isaac Campos 1, Brian Czaya 1, Kylie...

1Division of Nephrology, Department of Medicine, The University of Alabama at Bi...

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In-House Research
<p>Ionically Complexed Nanoparticles for Heparin Oral Delivery</p>

Ionically Complexed Nanoparticles for Heparin Oral Delivery

Bhagyashree Subramaniam, Nicole Leonick, Varenya Gade, David M. Frey, Fuming Zha...

Department of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, ...

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In-House Research
<p>Interactions of marine sulfated glycans with antithrombin and platelet factor 4</p>

Interactions of marine sulfated glycans with antithrombin and platelet factor 4

Wenjing Zhang, Weihua Jin, Vitor Hugo Pomin, Fuming Zhang, Robert J. Linhardt

1Department of Endocrinology, Sir Run Run Shaw Hospital, Zhejiang University Sch...

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In-House Research
<p>Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants</p>

Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants

Gelbach, Adrianne L., Fuming Zhang, Seok-Joon Kwon, John T. Bates, Andrew P. Far...

1Department of Biological Sciences, Center for Biotechnology and Interdisciplina...

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In-House Research
<p>Expedient Synthesis of a Library of Heparan Sulfate-Like &ldquo;Head-to-Tail&rdquo; Linked Multimers for Structure and Activity Relationship Studies</p>

Expedient Synthesis of a Library of Heparan Sulfate-Like “Head-to-Tail” Linked Multimers for Structure and Activity Relationship Studies

Dr. Jicheng Zhang, Dr. Li Liang, Dr. Weizhun Yang, Dr. Sherif Ramadan, Dr. Kedar...

Department of Chemistry, Michigan State University, East Lansing, MI 48824 USA

...
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In-House Research
<p>Enzymatic synthesis of low molecular weight heparins from&nbsp;<em>N</em>-sulfo heparosan depolymerized by heparanase or heparin lyase</p>

Enzymatic synthesis of low molecular weight heparins from N-sulfo heparosan depolymerized by heparanase or heparin lyase

Yanlei Yu a, Li Fu b e, Peng He b, Ke Xia b, Sony Varghese e, Jonathan Dordick c...

College of Pharmaceutical Science & Collaborative Innovation Center for Yangtze ...

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In-House Research
<p>Effect of high glucose on glycosaminoglycans in cultured retinal endothelial cells and rat retina</p>

Effect of high glucose on glycosaminoglycans in cultured retinal endothelial cells and rat retina

Gaganpreet Kaur, Yuefan Song, Ke Xia, Kevin McCarthy, Fuming Zhang, Robert J Lin...

Department of Molecular and Cellular Physiology, Louisiana State University Heal...

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