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Glycomaterials Chronicles

Explore curated research chronicles, originating experimental data, spectral analysis, and related open-access publications across carbohydrate materials research.

Open Access publications hosted on VTechWorks
In-House Research
<p>TREM2 on microglia cell surface binds to and forms functional binary complexes with heparan sulfate modified with 6-O-sulfation and iduronic acid</p>

TREM2 on microglia cell surface binds to and forms functional binary complexes with heparan sulfate modified with 6-O-sulfation and iduronic acid

Ilayda Ozsan McMillan, Li Liang, Guowei Su, Xuehong Song, Kelly Drago, Hua Yang,...

Division of Chemical Biology and Medicinal Chemistry, University of North Caroli...

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In-House Research
<p>Fibrolamellar Carcinomas&ndash;Growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides</p>

Fibrolamellar Carcinomas–Growth arrested by paracrine signals complexed with synthesized 3-O sulfated heparan sulfate oligosaccharides

Wencheng Zhang a b c d 1, Yongmei Xu e f 1 2, Xicheng Wang b c d 3, Tsunekazu Oi...

aDepartment of Cell Biology and Physiology, University of North Carolina, Chapel...

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In-House Research
<p>Dynamic Changes in Heparan Sulfate Nanostructure in Human Pluripotent Stem Cell Differentiation</p>

Dynamic Changes in Heparan Sulfate Nanostructure in Human Pluripotent Stem Cell Differentiation

Mahbuba, Deena Al; Masuko, Sayaka; Wang, Shiwei; Syangtan, Deepsing; Kang, Jeong...

Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts...

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In-House Research
<p>Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation</p>

Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation

Qi Zhang, Weichun Tang, Eduardo Stancanelli, Eunkyung Jung, Zulfeqhar Syed, Vija...

1 Laboratory of Molecular Biology, National Institute of Diabetes, Digestive, an...

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In-House Research
<p>Seaweed-derived fucoidans and rhamnan sulfates serve as potent anti-SARS-CoV-2 agents with potential for prophylaxis</p>

Seaweed-derived fucoidans and rhamnan sulfates serve as potent anti-SARS-CoV-2 agents with potential for prophylaxis

Yuefan Song a, Amit Singh b, Maisha M. Feroz a c, Shirley Xu a c, Fuming Zhang a...

a Center for Biotechnology & Interdisciplinary Studies, Rensselaer Polytechnic I...

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In-House Research
<p>Developing a solid-phase method for the enzymatic synthesis of heparan sulfate and chondroitin sulfate backbones</p>

Developing a solid-phase method for the enzymatic synthesis of heparan sulfate and chondroitin sulfate backbones

Stancanelli, Eduardo; Liu, Wei; Su, Guowei; Padagala, Vijay; Liu, Jian

  • 1Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pha...
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In-House Research
<p>Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin</p>

Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin

J. Yang; Y. Song; W. Jin; K. Xia; G. C. Burnett; W. Qiao; J. T. Bates; V. H. Pom...

1The Key Laboratory of Molecular Microbiology and Technology, Ministry of Educat...

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In-House Research
<p>Inhibition of sulfated glycans on the binding of dengue virus envelope protein to heparin</p>

Inhibition of sulfated glycans on the binding of dengue virus envelope protein to heparin

Jiyuan Yang, Payel Datta, Ke Xia, Vitor H. Pomin, Chunyu Wang, Mingqiang Qiao, R...

Departments of Chemical and Biological Engineering, Rensselaer Polytechnic Insti...

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In-House Research
<p>Applications of Surface Plasmon Resonance in Heparan Sulfate Interactome Research</p>

Applications of Surface Plasmon Resonance in Heparan Sulfate Interactome Research

Payel Datta, Jonathan S. Dordick, Fuming Zhang

Department of Chemical and Biological Engineering, Center for Biotechnology and ...

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In-House Research
<p>Marine-derived sulfated glycans display a potent virostatic mechanism to block herpes simplex virus type-1 (HSV-1) entry and spread</p>

Marine-derived sulfated glycans display a potent virostatic mechanism to block herpes simplex virus type-1 (HSV-1) entry and spread

James Elste, Michele Rabbitt, Chunyu Wang, Jonathan S. Dordick, Vaibhav Tiwari, ...

Department of Microbiology & Immunology, College of Graduate Studies, Midwestern...

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In-House Research
<p>Thermodynamics of calcium binding to heparin: Implications of solvation and water structuring for polysaccharide biofunctions</p>

Thermodynamics of calcium binding to heparin: Implications of solvation and water structuring for polysaccharide biofunctions

Brenna M. Knight,  Connor M. B. Gallagher, Michael D. Schulz, Kevin J. Edgar, Ca...

Department of Chemistry, Virginia Tech, Blacksburg, VA 24061
Macromolecules Inn...
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In-House Research
<p>Structural Characteristics of Heparin Binding to SARS-CoV-2 Spike Protein RBD of Omicron Sub-Lineages BA.2.12.1, BA.4 and BA.5</p>

Structural Characteristics of Heparin Binding to SARS-CoV-2 Spike Protein RBD of Omicron Sub-Lineages BA.2.12.1, BA.4 and BA.5

Deling Shi1,2, Changkai Bu1, Peng He2, Yuefan Song2, Jonathan S. Dordick2, Rober...

1National Glycoengineering Research Center, Shandong University, Qingdao 266237,...

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In-House Research
<p>Chemoenzymatic synthesis of sulfur-linked sugar polymers as heparanase inhibitors</p>

Chemoenzymatic synthesis of sulfur-linked sugar polymers as heparanase inhibitors

Peng He, Xing Zhang, Ke Xia, Dixy E. Green, Sultan Baytas, Yongmei Xu, Truong Ph...

Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic I...

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In-House Research
<p>The diverse role of heparan sulfate and other GAGs in SARS-CoV-2 infections and therapeutics</p>

The diverse role of heparan sulfate and other GAGs in SARS-CoV-2 infections and therapeutics

Friederike Eilts a b 1, Sarah Bauer a 1, Keith Fraser c 1, Jonathan S. Dordick a...

aDepartment of Chemical and Biological Engineering, Center for Biotechnology and...

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In-House Research
<p>Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants</p>

Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants

Gelbach, Adrianne L., Fuming Zhang, Seok-Joon Kwon, John T. Bates, Andrew P. Far...

1Department of Biological Sciences, Center for Biotechnology and Interdisciplina...

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In-House Research
<p>Expedient Synthesis of a Library of Heparan Sulfate-Like &ldquo;Head-to-Tail&rdquo; Linked Multimers for Structure and Activity Relationship Studies</p>

Expedient Synthesis of a Library of Heparan Sulfate-Like “Head-to-Tail” Linked Multimers for Structure and Activity Relationship Studies

Dr. Jicheng Zhang, Dr. Li Liang, Dr. Weizhun Yang, Dr. Sherif Ramadan, Dr. Kedar...

Department of Chemistry, Michigan State University, East Lansing, MI 48824 USA

...
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In-House Research
<p>Effect of high glucose on glycosaminoglycans in cultured retinal endothelial cells and rat retina</p>

Effect of high glucose on glycosaminoglycans in cultured retinal endothelial cells and rat retina

Gaganpreet Kaur, Yuefan Song, Ke Xia, Kevin McCarthy, Fuming Zhang, Robert J Lin...

Department of Molecular and Cellular Physiology, Louisiana State University Heal...

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In-House Research
<p>Chemoenzymatic Synthesis of Homogeneous Heparan Sulfate and Chondroitin Sulfate Chimeras</p>

Chemoenzymatic Synthesis of Homogeneous Heparan Sulfate and Chondroitin Sulfate Chimeras

Eduardo Stancanelli, Wei Liu, Rylee Wander, Jine Li, Zhangjie Wang, Katelyn Arno...

Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmac...

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In-House Research
<p>Structural and Substrate Specificity Analysis of 3-<em>O</em>-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate</p>

Structural and Substrate Specificity Analysis of 3-O-Sulfotransferase Isoform 5 to Synthesize Heparan Sulfate

Rylee Wander, Andrea M. Kaminski, Zhangjie Wang, Eduardo Stancanelli, Yongmei Xu...

Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmac...

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In-House Research
<p>Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate</p>

Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate

Fuming Zhang1,*, Peng He2, Andre L. Rodrigues1, Walter Jeske3, Ritesh Tandon4,5,...

  1. Department of Chemical and Biological Engineering, Center for Biotechnology a...
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