PhD Opportunity: The ORIGAMI Project (36 months, fully funded) at Université de Lille (France) and Nagoya University (Japan) is seeking a motivated candidate to investigate O-GlcNAcylation, a nutrient-sensitive post-translational modification influencing chromatin folding, gene transcription, metabolism, and cancer development. This multidisciplinary project offers comprehensive training in molecular biology, glycobiology, computational biology, and advanced omics technologies.

Key research methodologies include:
• Chromatin mapping using Hi-C
• Transcriptomic profiling via RNA-seq
• Genome editing with CRISPR/Cas9 and the use of iPSC/organoid models
• Multi-omics data analysis with artificial intelligence integration

Requirements:
• Master’s degree in molecular biology, biochemistry, bioinformatics, or a related field
• Practical skills in molecular biology (e.g., CRISPR/Cas9, iPSC/organoid culture)
• Experience with omics technologies (RNA-seq, Hi-C, Cut&Tag, ChIP-seq)
• Basic proficiency in bioinformatics (R, Python)
• Excellent command of English (written and spoken)
• Demonstrated motivation for interdisciplinary and international research

Research Environment:
• Université de Lille: Renowned for excellence in life sciences, glycobiology, cancer biology, and data science.
• UGSF (Unité de Glycobiologie Structurale et Fonctionnelle): Leading European institute in glyco-epigenetics and cancer.
• Nagoya University: Premier Japanese center for biomedical sciences, specializing in genome regulation and cancer.
• PLBS & iCORE: Providing advanced support in omics technologies, screening, and data analysis.

Funding and Benefits:
• Fully funded by the WILL International Chair and France 2030 initiative
• Competitive stipend as per French doctoral contracts
• Travel and accommodation support for research stays in Japan
• Access to international training programs, seminars, and workshops

Application Procedure:
Submit your application by August 15, 2025, including:
• Curriculum Vitae with academic transcripts
• Motivation letter
• Two academic references

Send applications to:
stephan.hardiville@univ-lille.fr and hisuzuki@med.nagoya-u.ac.jp

Shortlisted candidates will be contacted for interviews in early September.