HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept
{
"count": 124,
"next": "http://glycodata.org/api/gdd/glass-transition-temperatures/?format=api&page=6",
"previous": "http://glycodata.org/api/gdd/glass-transition-temperatures/?format=api&page=4",
"results": [
{
"id": 81,
"substance": "Galactose",
"glass_transition_temperature": "30",
"doi": "10.1111/j.1541-4337.2010.00136.x",
"method": "Experiment",
"conditions": "DSC anhydrous (Table 4, completely dried glass)",
"conditions_detail": "DSC anhydrous (Table 4, completely dried glass) | water: anhydrous (0 wt%); MW (g/mol): 180.16",
"comments": "\"Table 4-T g values for various sweeteners (assumes completely dried glass) (from Ergun and others 2010). ... Galactose ... 30\" Table 4 row Galactose, Tg = 30 C. [reported: 30 C; confidence: high; Hartel RW, Ergun R, Vogel S (2011)]"
},
{
"id": 82,
"substance": "Sorbitol",
"glass_transition_temperature": "-9",
"doi": "10.1111/j.1541-4337.2010.00136.x",
"method": "Experiment",
"conditions": "DSC anhydrous (Table 4, completely dried glass)",
"conditions_detail": "DSC anhydrous (Table 4, completely dried glass) | water: anhydrous (0 wt%); MW (g/mol): 182.17",
"comments": "\"Table 4-T g values for various sweeteners (assumes completely dried glass) ... Sorbitol ... -9\" Table 4 row Sorbitol, Tg = -9 C. [reported: -9 C; confidence: high; Hartel RW, Ergun R, Vogel S (2011)]"
},
{
"id": 83,
"substance": "Sorbitol",
"glass_transition_temperature": "-9.20 to -6.0",
"doi": "10.3390/pharmaceutics15112557",
"method": "Experiment",
"conditions": "DSC anhydrous (reported range -9.20 to -6.0)",
"conditions_detail": "DSC anhydrous (reported range -9.20 to -6.0) | water: anhydrous (0 wt%); MW (g/mol): 182.17",
"comments": "\"Sorbitol ... -9.20--6.0\" Table 3 polyol physicochemical properties; Tg reported as range -9.20 to -6.0 C. [reported: -9.20 to -6.0 C; confidence: high; Poka MS, Milne M, Wessels A, Aucamp M (2023)]"
},
{
"id": 84,
"substance": "Sorbitol",
"glass_transition_temperature": "-4.1",
"doi": "10.1063/1.5037305",
"method": "Experiment",
"conditions": "DSC, onset Tg on heating at 10 K/min after cooling at 10...",
"conditions_detail": "DSC, onset Tg on heating at 10 K/min after cooling at 10 K/min (anhydrous D-sorbitol) | water: anhydrous (0 wt%); MW (g/mol): 182.17",
"comments": "\"D-sorbitol 269 353 26.7\" Table 1, Tg(K)=269. Tg is onset during heating at 10 K/min, following cooling at 10 K/min. Value attributed to Ref. 22. [reported: 269 K; confidence: high; Huang C, Chen Z, Gui Y, Shi C, Zhang GGZ, Yu L (2018)]"
},
{
"id": 85,
"substance": "Xylitol",
"glass_transition_temperature": "-29",
"doi": "10.1111/j.1541-4337.2010.00136.x",
"method": "Experiment",
"conditions": "DSC anhydrous (Table 4, completely dried glass)",
"conditions_detail": "DSC anhydrous (Table 4, completely dried glass) | water: anhydrous (0 wt%); MW (g/mol): 152.15",
"comments": "\"Table 4-T g values for various sweeteners (assumes completely dried glass) ... Xylitol ... -29\" Table 4 row Xylitol, Tg = -29 C. [reported: -29 C; confidence: high; Hartel RW, Ergun R, Vogel S (2011)]"
},
{
"id": 86,
"substance": "Xylitol",
"glass_transition_temperature": "-24.1",
"doi": "10.3390/pharmaceutics15112557",
"method": "Experiment",
"conditions": "DSC anhydrous",
"conditions_detail": "DSC anhydrous | water: anhydrous (0 wt%); MW (g/mol): 152.15",
"comments": "\"Xylitol ... -24.10\" Table 3 polyol physicochemical properties; Tg = -24.10 C. [reported: -24.1 C; confidence: high; Poka MS, Milne M, Wessels A, Aucamp M (2023)]"
},
{
"id": 87,
"substance": "Xylitol",
"glass_transition_temperature": "-23.1",
"doi": "10.1063/1.5037305",
"method": "Experiment",
"conditions": "DSC, onset Tg on heating at 10 K/min after cooling at 10...",
"conditions_detail": "DSC, onset Tg on heating at 10 K/min after cooling at 10 K/min (anhydrous D-xylitol) | water: anhydrous (0 wt%); MW (g/mol): 152.15",
"comments": "\"D-xylitol 250 366 37.3 (0.7)\" Table 1, Tg(K)=250 ('This work'). Onset, 10 K/min. [reported: 250 K; confidence: high; Huang C, Chen Z, Gui Y, Shi C, Zhang GGZ, Yu L (2018)]"
},
{
"id": 88,
"substance": "Mannitol",
"glass_transition_temperature": "10.7",
"doi": "10.1021/js970224o",
"method": "Experiment",
"conditions": "DSC, Tg onset (glass properties of D-mannitol via extrapo...",
"conditions_detail": "DSC, Tg onset (glass properties of D-mannitol via extrapolation using sorbitol as impurity) | water: anhydrous (0 wt%); MW (g/mol): 182.17",
"comments": "\"Tg onset = 10.7 C, Tg midpoint = 12.6 C, Tg end = 18.4 degC\" Mannitol Tg obtained by extrapolation to zero sorbitol because mannitol crystallizes too readily to measure directly. Onset 10.7, midpoint 12.6, end 18.4 C. [reported: 10.7 C; confidence: high; Yu L, Mishra DS, Rigsbee DR (1998)]"
},
{
"id": 89,
"substance": "Mannitol",
"glass_transition_temperature": "10.7",
"doi": "10.3390/pharmaceutics15112557",
"method": "Experiment",
"conditions": "DSC anhydrous",
"conditions_detail": "DSC anhydrous | water: anhydrous (0 wt%); MW (g/mol): 182.17",
"comments": "\"Mannitol ... 10.7\" Table 3 polyol physicochemical properties; Tg = 10.7 C (consistent with Yu et al. 1998). [reported: 10.7 C; confidence: high; Poka MS, Milne M, Wessels A, Aucamp M (2023)]"
},
{
"id": 90,
"substance": "Maltitol",
"glass_transition_temperature": "39",
"doi": "10.1111/j.1541-4337.2010.00136.x",
"method": "Experiment",
"conditions": "DSC anhydrous (Table 4, completely dried glass)",
"conditions_detail": "DSC anhydrous (Table 4, completely dried glass) | water: anhydrous (0 wt%); MW (g/mol): 344.31",
"comments": "\"Table 4-T g values for various sweeteners (assumes completely dried glass) ... Maltitol ... 39\" Table 4 row Maltitol, Tg = 39 C. Maltitol is a disaccharide polyol. [reported: 39 C; confidence: high; Hartel RW, Ergun R, Vogel S (2011)]"
},
{
"id": 91,
"substance": "Maltitol",
"glass_transition_temperature": "43.1 to 49.5",
"doi": "10.3390/pharmaceutics15112557",
"method": "Experiment",
"conditions": "DSC anhydrous (reported range)",
"conditions_detail": "DSC anhydrous (reported range) | water: anhydrous (0 wt%); MW (g/mol): 344.31",
"comments": "\"Maltitol ... 43.1-49.5\" Table 3 polyol physicochemical properties; Tg range 43.1 to 49.5 C. [reported: 43.1 to 49.5 C; confidence: high; Poka MS, Milne M, Wessels A, Aucamp M (2023)]"
},
{
"id": 92,
"substance": "Erythritol",
"glass_transition_temperature": "-45.0 to -42.50",
"doi": "10.3390/pharmaceutics15112557",
"method": "Experiment",
"conditions": "DSC anhydrous (reported range)",
"conditions_detail": "DSC anhydrous (reported range) | water: anhydrous (0 wt%); MW (g/mol): 122.12",
"comments": "\"Erythritol ... -45.0--42.50\" Table 3 polyol physicochemical properties; Tg range -45.0 to -42.50 C. Erythritol crystallizes rapidly so direct glass measurement is difficult. [reported: -45.0 to -42.50 C; confidence: high; Poka MS, Milne M, Wessels A, Aucamp M (2023)]"
},
{
"id": 93,
"substance": "Glycerol",
"glass_transition_temperature": "-84.1",
"doi": "10.1063/1.5037305",
"method": "Experiment",
"conditions": "DSC, onset Tg on heating at 10 K/min after cooling at 10...",
"conditions_detail": "DSC, onset Tg on heating at 10 K/min after cooling at 10 K/min (anhydrous glycerol) | water: anhydrous (0 wt%); MW (g/mol): 92.09",
"comments": "\"Glycerol 189 291 18.3\" Table 1, Tg(K)=189. Attributed to Refs. 20,21. ~ -84 C. [reported: 189 K; confidence: high; Huang C, Chen Z, Gui Y, Shi C, Zhang GGZ, Yu L (2018)]"
},
{
"id": 94,
"substance": "Glycerol",
"glass_transition_temperature": "-84",
"doi": "10.1039/D1CP02153B",
"method": "Experiment",
"conditions": "DSC onset Tg, pure glycerol (bulk sample)",
"conditions_detail": "DSC onset Tg, pure glycerol (bulk sample) | water: anhydrous (0 wt%); MW (g/mol): 92.09",
"comments": "\"189.1 +/- 1 K (bulk sample)\" Pure glycerol onset Tg from Table 2 (bulk). Value reported as 189.1 +/- 1 K. [reported: 189.1 K; confidence: medium; Angarita I, Mazzobre MF, Corti HR, Longinotti MP (2021)]"
},
{
"id": 95,
"substance": "Arabitol",
"glass_transition_temperature": "-13.1",
"doi": "10.1063/1.5037305",
"method": "Experiment",
"conditions": "DSC, onset Tg on heating at 10 K/min after cooling at 10...",
"conditions_detail": "DSC, onset Tg on heating at 10 K/min after cooling at 10 K/min (anhydrous D-arabitol) | water: anhydrous (0 wt%); MW (g/mol): 152.15",
"comments": "\"D-arabitol 260 376 39.9 (0.2)\" Table 1, Tg(K)=260 ('This work'). Onset, 10 K/min. [reported: 260 K; confidence: high; Huang C, Chen Z, Gui Y, Shi C, Zhang GGZ, Yu L (2018)]"
},
{
"id": 96,
"substance": "Dextran",
"glass_transition_temperature": "151.8",
"doi": "10.3390/pharmaceutics12060483",
"method": "Experiment",
"conditions": "DSC, MW 1.0 kDa; Tg vs molecular weight series (data from...",
"conditions_detail": "DSC, MW 1.0 kDa; Tg vs molecular weight series (data from Larsen et al. 2018) | MW (g/mol): 1000",
"comments": "\"1.0 kDa ... 151.8 +/- 0.2 (Tg, C)\" Table 1; Tg of dextran fraction; original source Larsen et al., Pharm Dev Technol 2018, doi:10.1080/10837450.2018.1479866. Hydration state not explicitly stated. [reported: 151.8 C; confidence: high; Asgreen C, Knopp MM, Skytte J, Lobmann K (2020)]"
},
{
"id": 97,
"substance": "Dextran",
"glass_transition_temperature": "162.4",
"doi": "10.3390/pharmaceutics12060483",
"method": "Experiment",
"conditions": "DSC, MW 1.6 kDa; Tg vs molecular weight series",
"conditions_detail": "DSC, MW 1.6 kDa; Tg vs molecular weight series | MW (g/mol): 1600",
"comments": "\"1.6 kDa ... 162.4 +/- 1.1 (Tg, C)\" Table 1; original source Larsen et al. 2018. [reported: 162.4 C; confidence: high; Asgreen C, Knopp MM, Skytte J, Lobmann K (2020)]"
},
{
"id": 98,
"substance": "Dextran",
"glass_transition_temperature": "194.8",
"doi": "10.3390/pharmaceutics12060483",
"method": "Experiment",
"conditions": "DSC, MW 3.7 kDa; Tg vs molecular weight series",
"conditions_detail": "DSC, MW 3.7 kDa; Tg vs molecular weight series | MW (g/mol): 3700",
"comments": "\"3.7 kDa ... 194.8 +/- 0.4 (Tg, C)\" Table 1; original source Larsen et al. 2018. [reported: 194.8 C; confidence: high; Asgreen C, Knopp MM, Skytte J, Lobmann K (2020)]"
},
{
"id": 99,
"substance": "Dextran",
"glass_transition_temperature": "204.4",
"doi": "10.3390/pharmaceutics12060483",
"method": "Experiment",
"conditions": "DSC, MW 5.2 kDa; Tg vs molecular weight series",
"conditions_detail": "DSC, MW 5.2 kDa; Tg vs molecular weight series | MW (g/mol): 5200",
"comments": "\"5.2 kDa ... 204.4 +/- 0.8 (Tg, C)\" Table 1; original source Larsen et al. 2018. [reported: 204.4 C; confidence: high; Asgreen C, Knopp MM, Skytte J, Lobmann K (2020)]"
},
{
"id": 100,
"substance": "Dextran",
"glass_transition_temperature": "212.8",
"doi": "10.3390/pharmaceutics12060483",
"method": "Experiment",
"conditions": "DSC, MW 9.6 kDa; Tg vs molecular weight series",
"conditions_detail": "DSC, MW 9.6 kDa; Tg vs molecular weight series | MW (g/mol): 9600",
"comments": "\"9.6 kDa ... 212.8 +/- 0.9 (Tg, C)\" Table 1; original source Larsen et al. 2018. [reported: 212.8 C; confidence: high; Asgreen C, Knopp MM, Skytte J, Lobmann K (2020)]"
}
]
}