{"count":839,"next":"http://glycodata.org/api/gdd/glyco-properties/?format=json&page=32","previous":"http://glycodata.org/api/gdd/glyco-properties/?format=json&page=30","results":[{"id":601,"dataset":"cellulose","entity":"regenerated cellulose fiber (lyocell)","entity_group":"lyocell/Tencel","entity_class":"regenerated cellulose","property":"glass transition temperature","property_key":"Tg","value":"239.85","unit":"C","value_reported":"513","unit_reported":"K","method":"Experiment","method_detail":"DMA; Tg of dry fiber from tan delta; water plasticizes Tg to room temperature at water regain ~56%","conditions":"DMA; Tg of dry fiber from tan delta; water plasticizes Tg to room temperature at water regain ~56%","conditions_detail":"DMA; Tg of dry fiber from tan delta; water plasticizes Tg to room temperature at water regain ~56% | test state: dry | water (wt%): 0","doi":"10.1016/j.carbpol.2019.115663","source_url":"https://doi.org/10.1016/j.carbpol.2019.115663","year":"2020","confidence":"medium","comments":"\"The glass transition temperature (Tg) of dry regenerated cellulose is 552 K for rayon, 523 K for cupra, and 513 K for lyocell\"  — Dry lyocell regenerated cellulose Tg = 513 K (DMA). Tg falls to room temperature at ~56% water regain. Cellulose II.  [Okugawa A, Sakaino M, Yuguchi Y, et al., 2020, confidence: medium]"},{"id":602,"dataset":"cellulose","entity":"regenerated cellulose film (dry)","entity_group":"regenerated cellulose (other)","entity_class":"regenerated cellulose","property":"glass transition temperature","property_key":"Tg","value":"126.85","unit":"C","value_reported":"400","unit_reported":"K","method":"Review","method_detail":"linear dilatometry of dry regenerated-cellulose film; alpha2 secondary glass transition near 400 K (390-410 K) and beta transition near 280-300 K","conditions":"linear dilatometry of dry regenerated-cellulose film; alpha2 secondary glass transition near 400 K (390-410 K) and beta transition near 280-300 K","conditions_detail":"linear dilatometry of dry regenerated-cellulose film; alpha2 secondary glass transition near 400 K (390-410 K) and beta transition near 280-300 K | test state: dry | water (wt%): 0","doi":"10.30958/ajs.3-4-4","source_url":"https://www.athensjournals.gr/sciences/2016-3-4-4-Ioelovich.pdf","year":"2016","confidence":"low","comments":"\"Figure 3. Linear Dilatometry of Dry Film of Regenerated Cellulose ... the temperatures 390-410 K, the alpha2-relaxation transition was discovered ... The third relaxation transition was detected at the temperatures 280-300 K (beta).\"  — Dry regenerated-cellulose film dilatometry shows alpha2 secondary glass transition ~390-410 K (value 400 K) and beta ~280-300 K. Cellulose II. Estimate from dilatometry inflection.  [Ioelovich M, 2016, confidence: low]"},{"id":603,"dataset":"cellulose","entity":"CNC-doped cellulose triacetate (TAC) optical film","entity_group":"cellulose acetate","entity_class":"nanocellulose","property":"glass transition temperature","property_key":"Tg","value":"215.5","unit":"C","value_reported":"215-216","unit_reported":"C","method":"Experiment","method_detail":"glass transition temperature of CNC-doped cellulose triacetate films (TAC-X, 0-2 wt% CNC); thermal characterization (DSC/TGA)","conditions":"glass transition temperature of CNC-doped cellulose triacetate films (TAC-X, 0-2 wt% CNC); thermal characterization (DSC/TGA)","conditions_detail":"glass transition temperature of CNC-doped cellulose triacetate films (TAC-X, 0-2 wt% CNC); thermal characterization (DSC/TGA) | test state: cast nanocomposite film","doi":"10.1002/slct.202400262","source_url":"https://doi.org/10.1002/slct.202400262","year":"2024","confidence":"medium","comments":"\"its glass transition temperature and maximum decomposition temperature falling between 215-216 °C and 366-368 °C respectively.\"  — Matrix is cellulose triacetate (a cellulose derivative) doped with up to 2 wt% CNC; Tg essentially that of the TAC phase, nearly unchanged by CNC. Both components cellulosic.  [Zhou Y, Tang S, Zhang Q, Tan L, et al., 2024, confidence: medium]"},{"id":604,"dataset":"cellulose","entity":"microcrystalline cellulose (dehydrated)","entity_group":"microcrystalline cellulose (MCC)","entity_class":"pulp / microcrystalline cellulose","property":"glass transition temperature","property_key":"Tg","value":"84.0","unit":"C","value_reported":"84","unit_reported":"C","method":"Experiment","method_detail":"DSC, heat-capacity step on reheat after 4 consecutive dehydration cycles, dry (anhydrous) cellulose; delta-Cp = 0.30 ± 0.01 J/(g·C)","conditions":"DSC, heat-capacity step on reheat after 4 consecutive dehydration cycles, dry (anhydrous) cellulose; delta-Cp = 0.30 ± 0.01 J/(g·C)","conditions_detail":"DSC, heat-capacity step on reheat after 4 consecutive dehydration cycles, dry (anhydrous) cellulose; delta-Cp = 0.30 ± 0.01 J/(g·C) | heating rate (K/min): 20 | test state: dehydrated microcrystalline cellulose | water (wt%): 0","doi":"10.1088/0022-3727/44/4/045403","source_url":"https://hal.science/hal-00589771","year":"2011","confidence":"high","comments":"\"The Tg of dehydrated cellulose is found at 84 ± 1°C with a delta-Cp = 0.30 ± 0.01 J/(g.°C).\"  — Microcrystalline cellulose powder/pellets, fully dehydrated. Tg decreases strongly with hydration; hydrated runs (0-5% water) recorded at 20 C/min. Green OA via HAL.  [Roig F, Dantras E, Dandurand J, Lacabanne C, 2011, confidence: high]"},{"id":605,"dataset":"cellulose","entity":"cellulose (dry ball-milled wood pulp; eucalyptus/softwood)","entity_group":"dissolving/wood pulp","entity_class":"pulp / microcrystalline cellulose","property":"glass transition temperature","property_key":"Tg","value":"204.85","unit":"C","value_reported":"478","unit_reported":"K","method":"Model","method_detail":"DMA 'pocket' technique on water-content series; dry-cellulose Tg by Couchman-Karasz extrapolation to 0% water","conditions":"DMA 'pocket' technique on water-content series; dry-cellulose Tg by Couchman-Karasz extrapolation to 0% water","conditions_detail":"DMA 'pocket' technique on water-content series; dry-cellulose Tg by Couchman-Karasz extrapolation to 0% water | test state: dry ball-milled cellulose (extrapolated) | water (wt%): 0","doi":"10.1007/s10570-010-9425-7","source_url":"https://doi.org/10.1007/s10570-010-9425-7","year":"2010","confidence":"medium","comments":"\"Fitting the data to a Couchman-Karasz relationship predicted a value for Tg of the dry cellulose of approximately 478 K, which was similar to values previously reported for other dry polysaccharides.\"  — Model extrapolation (Couchman-Karasz) of water-content-dependent DMA transition to dry state; measured over 5-42% db water. Pulp source. (Same study as the native-cellulose 478 K record; listed under pulp/MCC for the pulp framing.)  [Paes SS, Sun S, MacNaughtan W, Ibbett R, Ganster J, Foster TJ, Mitchell JR, 2010, confidence: medium]"},{"id":606,"dataset":"cellulose","entity":"amorphous region of cellulose (dry)","entity_group":"cellulose (generic)","entity_class":"pulp / microcrystalline cellulose","property":"glass transition temperature","property_key":"Tg","value":"225.0","unit":"C","value_reported":"200-250","unit_reported":"C","method":"Review","method_detail":"Literature compilation (citing Back and Salmen 1982) of dry-state softening/glass transition ranges for wood polymers","conditions":"Literature compilation (citing Back and Salmen 1982) of dry-state softening/glass transition ranges for wood polymers","conditions_detail":"Literature compilation (citing Back and Salmen 1982) of dry-state softening/glass transition ranges for wood polymers | test state: dry amorphous cellulose | water (wt%): 0","doi":"10.15376/biores.6.2.2125-2134","source_url":"https://doi.org/10.15376/biores.6.2.2125-2134","year":"2011","confidence":"high","comments":"\"When dry, the differences in glass transition temperature are not huge: 200 to 250 °C for the amorphous region of cellulose, 150 to 220 °C for hemicelluloses, and 205 °C for lignin (Back and Salmén 1982).\"  — Review/compilation value for canonical dry amorphous-cellulose Tg range. At water-saturated conditions Tg drops to subambient. (Duplicate framing of the native-cellulose record; pulp/wood context.)  [Horvath B, Peralta PN, Frazier CE, Peszlen I, 2011, confidence: high]"},{"id":607,"dataset":"heparin","entity":"heparin (UFH) - porcine mucosal","entity_group":"","entity_class":"heparin (UFH)","property":"anti-IIa activity","property_key":"anti_iia_activity","value":"183.4","unit":"IU/mg","value_reported":"183.4","unit_reported":"IU/mg","method":"Experiment","method_detail":"antithrombin-dependent anti-IIa (AT:aIIa) amidolytic assay vs USP heparin reference standard","conditions":"antithrombin-dependent anti-IIa (AT:aIIa) amidolytic assay vs USP heparin reference standard","conditions_detail":"antithrombin-dependent anti-IIa (AT:aIIa) amidolytic assay vs USP heparin reference standard | source species: porcine intestinal mucosa | assay: AT-dependent amidolytic | uncertainty: +/-1.7 SD","doi":"10.3389/fmed.2018.00360","source_url":"https://doi.org/10.3389/fmed.2018.00360","year":"2019","confidence":"high","comments":"\"Porcine heparins exhibited mean anti-Xa and anti-IIa potencies of 184.6 +/- 2.8 and 183.4 +/- 1.7 U/mg, respectively.\"  — Directly-stated anti-IIa specific activity for porcine mucosal heparin API.  [Jeske W, Kouta A, Farooqui A, et al., 2019, confidence: high]"},{"id":608,"dataset":"heparin","entity":"heparin (UFH) - bovine mucosal","entity_group":"","entity_class":"heparin (UFH)","property":"anti-IIa activity","property_key":"anti_iia_activity","value":"133","unit":"IU/mg","value_reported":"133.0","unit_reported":"IU/mg","method":"Experiment","method_detail":"antithrombin-dependent anti-IIa (AT:aIIa) amidolytic assay vs USP heparin reference standard","conditions":"antithrombin-dependent anti-IIa (AT:aIIa) amidolytic assay vs USP heparin reference standard","conditions_detail":"antithrombin-dependent anti-IIa (AT:aIIa) amidolytic assay vs USP heparin reference standard | source species: bovine intestinal mucosa | assay: AT-dependent amidolytic | uncertainty: +/-7.5 SD","doi":"10.3389/fmed.2018.00360","source_url":"https://doi.org/10.3389/fmed.2018.00360","year":"2019","confidence":"high","comments":"\"The potencies of bovine heparin were significantly lower at 132.4 +/- 5.0 and 133.0 +/- 7.5, respectively, based on anti-Xa and anti-IIa activity (p = 0.003 for anti-Xa and anti-IIa, Mann-Whitney test).\"  — Directly-stated anti-IIa specific activity for bovine mucosal heparin API; lower than porcine.  [Jeske W, Kouta A, Farooqui A, et al., 2019, confidence: high]"},{"id":609,"dataset":"heparin","entity":"heparin (UFH) - porcine mucosal","entity_group":"","entity_class":"heparin (UFH)","property":"anti-IIa activity","property_key":"anti_iia_activity","value":"107","unit":"IU/mg","value_reported":"107","unit_reported":"IU/mg","method":"Experiment","method_detail":"antithrombin-dependent anti-IIa (AT:aIIa) potency vs 6th International Standard for UFH, parallel-line bioassay","conditions":"antithrombin-dependent anti-IIa (AT:aIIa) potency vs 6th International Standard for UFH, parallel-line bioassay","conditions_detail":"antithrombin-dependent anti-IIa (AT:aIIa) potency vs 6th International Standard for UFH, parallel-line bioassay | source species: porcine intestinal mucosa | assay: AT-dependent anti-IIa | standard: 6th International Standard for UFH","doi":"10.3390/ph10030059","source_url":"https://doi.org/10.3390/ph10030059","year":"2017","confidence":"high","comments":"\"AT:aIIa potencies (107 IU/mg) were lower and the HCII:aIIa activities (165 IU/mg) were higher than AT:aXa and APTT estimates.\"  — AT-dependent anti-IIa potency (porcine heparin); contrasts with the higher HC-II-dependent value below.  [Hogwood J, Mulloy B, Gray E, 2017, confidence: high]"},{"id":610,"dataset":"heparin","entity":"heparin (UFH) - porcine mucosal","entity_group":"","entity_class":"heparin (UFH)","property":"anti-IIa activity","property_key":"anti_iia_activity","value":"165","unit":"IU/mg","value_reported":"165","unit_reported":"IU/mg","method":"Experiment","method_detail":"heparin cofactor II-dependent anti-IIa (HCII:aIIa) potency vs 6th International Standard for UFH","conditions":"heparin cofactor II-dependent anti-IIa (HCII:aIIa) potency vs 6th International Standard for UFH","conditions_detail":"heparin cofactor II-dependent anti-IIa (HCII:aIIa) potency vs 6th International Standard for UFH | source species: porcine intestinal mucosa | assay: HC-II-dependent anti-IIa | standard: 6th International Standard for UFH","doi":"10.3390/ph10030059","source_url":"https://doi.org/10.3390/ph10030059","year":"2017","confidence":"high","comments":"\"AT:aIIa potencies (107 IU/mg) were lower and the HCII:aIIa activities (165 IU/mg) were higher than AT:aXa and APTT estimates.\"  — Heparin cofactor II-dependent anti-IIa potency (porcine heparin).  [Hogwood J, Mulloy B, Gray E, 2017, confidence: high]"},{"id":611,"dataset":"heparin","entity":"heparin (UFH) - bovine lung","entity_group":"","entity_class":"heparin (UFH)","property":"anti-IIa activity","property_key":"anti_iia_activity","value":"127","unit":"IU/mg","value_reported":"127","unit_reported":"IU/mg","method":"Experiment","method_detail":"antithrombin-dependent anti-IIa (AT:aIIa) potency, mean of ten batches vs 6th International Standard for UFH","conditions":"antithrombin-dependent anti-IIa (AT:aIIa) potency, mean of ten batches vs 6th International Standard for UFH","conditions_detail":"antithrombin-dependent anti-IIa (AT:aIIa) potency, mean of ten batches vs 6th International Standard for UFH | source species: bovine lung | assay: AT-dependent anti-IIa | n batches: 10","doi":"10.3390/ph10030059","source_url":"https://doi.org/10.3390/ph10030059","year":"2017","confidence":"high","comments":"\"For ten batches of bovine lung heparin, the AT:aXa, AT:aIIa and APTT (130, 127, 121 IU/mg respectively) activities were similar (ANOVA, p > 0.01), but HCII:aIIa (220 IU/mg) activity was significantly higher than all other activities (ANOVA, p < 0.0001).\"  — AT-dependent anti-IIa for bovine lung heparin.  [Hogwood J, Mulloy B, Gray E, 2017, confidence: high]"},{"id":612,"dataset":"heparin","entity":"heparin (UFH) - bovine lung","entity_group":"","entity_class":"heparin (UFH)","property":"anti-IIa activity","property_key":"anti_iia_activity","value":"220","unit":"IU/mg","value_reported":"220","unit_reported":"IU/mg","method":"Experiment","method_detail":"heparin cofactor II-dependent anti-IIa (HCII:aIIa) potency, mean of ten batches vs 6th International Standard for UFH","conditions":"heparin cofactor II-dependent anti-IIa (HCII:aIIa) potency, mean of ten batches vs 6th International Standard for UFH","conditions_detail":"heparin cofactor II-dependent anti-IIa (HCII:aIIa) potency, mean of ten batches vs 6th International Standard for UFH | source species: bovine lung | assay: HC-II-dependent anti-IIa | n batches: 10","doi":"10.3390/ph10030059","source_url":"https://doi.org/10.3390/ph10030059","year":"2017","confidence":"high","comments":"\"but HCII:aIIa (220 IU/mg) activity was significantly higher than all other activities (ANOVA, p < 0.0001).\"  — Heparin cofactor II-dependent anti-IIa for bovine lung heparin.  [Hogwood J, Mulloy B, Gray E, 2017, confidence: high]"},{"id":613,"dataset":"heparin","entity":"rdLMWH-1 (rationally designed LMWH)","entity_group":"","entity_class":"LMWH","property":"anti-IIa activity","property_key":"anti_iia_activity","value":"230","unit":"IU/mg","value_reported":"230","unit_reported":"IU/mg","method":"Experiment","method_detail":"anti-IIa amidolytic activity of a rationally designed (enzymatically depolymerized) LMWH","conditions":"anti-IIa amidolytic activity of a rationally designed (enzymatically depolymerized) LMWH","conditions_detail":"anti-IIa amidolytic activity of a rationally designed (enzymatically depolymerized) LMWH | product: designer LMWH, not a marketed product","doi":"10.1073/pnas.252643299","source_url":"https://doi.org/10.1073/pnas.252643299","year":"2003","confidence":"high","comments":"\"rdLMWH-1 and -2 possessed significant anti-IIa activities of 230 IU/mg and 155 IU/mg, respectively.\"  — Engineered LMWH with unusually high anti-IIa; included for range context (not a commercial product).  [Sundaram M, Qi Y, Shriver Z, et al., 2003, confidence: high]"},{"id":614,"dataset":"heparin","entity":"rdLMWH-2 (rationally designed LMWH)","entity_group":"","entity_class":"LMWH","property":"anti-IIa activity","property_key":"anti_iia_activity","value":"155","unit":"IU/mg","value_reported":"155","unit_reported":"IU/mg","method":"Experiment","method_detail":"anti-IIa amidolytic activity of a rationally designed (enzymatically depolymerized) LMWH","conditions":"anti-IIa amidolytic activity of a rationally designed (enzymatically depolymerized) LMWH","conditions_detail":"anti-IIa amidolytic activity of a rationally designed (enzymatically depolymerized) LMWH | product: designer LMWH, not a marketed product","doi":"10.1073/pnas.252643299","source_url":"https://doi.org/10.1073/pnas.252643299","year":"2003","confidence":"high","comments":"\"rdLMWH-1 and -2 possessed significant anti-IIa activities of 230 IU/mg and 155 IU/mg, respectively.\"  — Engineered LMWH; included for range context (not a commercial product).  [Sundaram M, Qi Y, Shriver Z, et al., 2003, confidence: high]"},{"id":615,"dataset":"heparin","entity":"fondaparinux","entity_group":"","entity_class":"synthetic","property":"anti-IIa activity","property_key":"anti_iia_activity","value":"0","unit":"IU/mg","value_reported":"0","unit_reported":"IU/mg","method":"Review","method_detail":"synthetic pentasaccharide; selectively inhibits factor Xa only, no anti-IIa (thrombin) activity","conditions":"synthetic pentasaccharide; selectively inhibits factor Xa only, no anti-IIa (thrombin) activity","conditions_detail":"synthetic pentasaccharide; selectively inhibits factor Xa only, no anti-IIa (thrombin) activity | mechanism: too short to bridge antithrombin and thrombin","doi":"10.3390/ph16040584","source_url":"https://doi.org/10.3390/ph16040584","year":"2023","confidence":"medium","comments":"\"Conversely, inhibition of FXa requires only the binding of the pentasaccharide to AT-III, without the requirement for FXa to also bind to heparin. LMW heparins therefore have greater anti-Xa activity than anti-IIa activity.\"  — Fondaparinux (pentasaccharide) is too short to form the ternary anti-IIa bridge, so anti-IIa = 0; corroborates existing record.  [Shute JK, 2023, confidence: medium]"},{"id":616,"dataset":"heparin","entity":"heparin (UFH)","entity_group":"","entity_class":"heparin (UFH)","property":"anti-Xa activity","property_key":"anti_xa_activity","value":"200","unit":"IU/mg","value_reported":"180-220","unit_reported":"IU/mg","method":"Review","method_detail":"specific activity of current pharmaceutical UFH preparations","conditions":"specific activity of current pharmaceutical UFH preparations","conditions_detail":"specific activity of current pharmaceutical UFH preparations | avg MW Da: 13000-15000","doi":"10.3390/ph16040584","source_url":"https://doi.org/10.3390/ph16040584","year":"2023","confidence":"high","comments":"\"Current pharmaceutical preparations of UFH have an average molecular weight of about 13,000-15,000 Da and specific activity of 180-220 International Units (IU)/mg.\"  — Specific activity range; in heparin standardization anti-Xa and total potency are closely matched for UFH (~1:1 anti-Xa:anti-IIa).  [Shute JK, 2023, confidence: high]"},{"id":617,"dataset":"heparin","entity":"heparin (UFH) - porcine mucosal","entity_group":"","entity_class":"heparin (UFH)","property":"anti-Xa activity","property_key":"anti_xa_activity","value":"184.6","unit":"IU/mg","value_reported":"184.6","unit_reported":"IU/mg","method":"Experiment","method_detail":"antithrombin-dependent anti-Xa (AT:aXa) amidolytic assay vs USP heparin reference standard","conditions":"antithrombin-dependent anti-Xa (AT:aXa) amidolytic assay vs USP heparin reference standard","conditions_detail":"antithrombin-dependent anti-Xa (AT:aXa) amidolytic assay vs USP heparin reference standard | source species: porcine intestinal mucosa | uncertainty: +/-2.8 SD","doi":"10.3389/fmed.2018.00360","source_url":"https://doi.org/10.3389/fmed.2018.00360","year":"2019","confidence":"high","comments":"\"Porcine heparins exhibited mean anti-Xa and anti-IIa potencies of 184.6 +/- 2.8 and 183.4 +/- 1.7 U/mg, respectively.\"  — Companion anti-Xa value to the porcine anti-IIa record above.  [Jeske W, Kouta A, Farooqui A, et al., 2019, confidence: high]"},{"id":618,"dataset":"heparin","entity":"heparin (UFH) - bovine lung","entity_group":"","entity_class":"heparin (UFH)","property":"anti-Xa activity","property_key":"anti_xa_activity","value":"130","unit":"IU/mg","value_reported":"130","unit_reported":"IU/mg","method":"Experiment","method_detail":"antithrombin-dependent anti-Xa (AT:aXa) potency, mean of ten batches vs 6th International Standard for UFH","conditions":"antithrombin-dependent anti-Xa (AT:aXa) potency, mean of ten batches vs 6th International Standard for UFH","conditions_detail":"antithrombin-dependent anti-Xa (AT:aXa) potency, mean of ten batches vs 6th International Standard for UFH | source species: bovine lung | n batches: 10","doi":"10.3390/ph10030059","source_url":"https://doi.org/10.3390/ph10030059","year":"2017","confidence":"high","comments":"\"For ten batches of bovine lung heparin, the AT:aXa, AT:aIIa and APTT (130, 127, 121 IU/mg respectively) activities were similar (ANOVA, p > 0.01)\"  — Bovine lung heparin anti-Xa potency.  [Hogwood J, Mulloy B, Gray E, 2017, confidence: high]"},{"id":619,"dataset":"heparin","entity":"heparin (UFH) - chicken intestinal","entity_group":"","entity_class":"heparin (UFH)","property":"anti-Xa activity","property_key":"anti_xa_activity","value":"111","unit":"IU/mg","value_reported":"111","unit_reported":"IU/mg","method":"Review","method_detail":"specific anti-Xa activity of heparin extracted from chicken intestine","conditions":"specific anti-Xa activity of heparin extracted from chicken intestine","conditions_detail":"specific anti-Xa activity of heparin extracted from chicken intestine | source species: chicken intestine | S C ratio: 2.26","doi":"10.3390/molecules22061025","source_url":"https://doi.org/10.3390/molecules22061025","year":"2017","confidence":"high","comments":"\"Active heparin can be derived from chicken intestines with a specific aXa activity of 111 IU/mg and slightly lower degree of sulfation compared to porcine heparin produced according to the same method (S/C ratio resp.: 2.26 and 2.40).\"  — Non-mammalian (avian) heparin anti-Xa specific activity.  [van der Meer JY, Kellenbach E, van den Bos L, 2017, confidence: high]"},{"id":620,"dataset":"heparin","entity":"nadroparin","entity_group":"","entity_class":"LMWH","property":"anti-Xa activity","property_key":"anti_xa_activity","value":"112.5","unit":"IU/mg","value_reported":"95-130","unit_reported":"IU/mg","method":"Review","method_detail":"pharmacopoeial specification for nadroparin anti-Xa specific activity","conditions":"pharmacopoeial specification for nadroparin anti-Xa specific activity","conditions_detail":"pharmacopoeial specification for nadroparin anti-Xa specific activity | anti Xa anti IIa ratio: 2.5:1 to 4.0:1","doi":"","source_url":"https://www.sciencedirect.com/topics/nursing-and-health-professions/tinzaparin","year":"2020","confidence":"medium","comments":"\"Nadroparin comprises an anti-Xa activity of not less than 95 IU mg-1 and not more than 130 IU mg-1, and/or a ratio of anti-Xa activity to anti-IIa activity of at least 2.5:1, and up to 4.0:1.\"  — Pharmacopoeial anti-Xa specific-activity range for nadroparin (no DOI; ScienceDirect Topics compilation page).  [ScienceDirect Topics (compilation), 2020, confidence: medium]"}]}