{"count":124,"next":"http://glycodata.org/api/gdd/glass-transition-temperatures/?format=json&page=6","previous":"http://glycodata.org/api/gdd/glass-transition-temperatures/?format=json&page=4","results":[{"id":81,"substance":"Galactose","glass_transition_temperature":"30","doi":"10.1111/j.1541-4337.2010.00136.x","method":"Experiment","conditions":"DSC anhydrous (Table 4, completely dried glass)","conditions_detail":"DSC anhydrous (Table 4, completely dried glass) | water: anhydrous (0 wt%); MW (g/mol): 180.16","comments":"\"Table 4-T g values for various sweeteners (assumes completely dried glass) (from Ergun and others 2010). ... Galactose ... 30\" Table 4 row Galactose, Tg = 30 C. [reported: 30 C; confidence: high; Hartel RW, Ergun R, Vogel S (2011)]"},{"id":82,"substance":"Sorbitol","glass_transition_temperature":"-9","doi":"10.1111/j.1541-4337.2010.00136.x","method":"Experiment","conditions":"DSC anhydrous (Table 4, completely dried glass)","conditions_detail":"DSC anhydrous (Table 4, completely dried glass) | water: anhydrous (0 wt%); MW (g/mol): 182.17","comments":"\"Table 4-T g values for various sweeteners (assumes completely dried glass) ... Sorbitol ... -9\" Table 4 row Sorbitol, Tg = -9 C. [reported: -9 C; confidence: high; Hartel RW, Ergun R, Vogel S (2011)]"},{"id":83,"substance":"Sorbitol","glass_transition_temperature":"-9.20 to -6.0","doi":"10.3390/pharmaceutics15112557","method":"Experiment","conditions":"DSC anhydrous (reported range -9.20 to -6.0)","conditions_detail":"DSC anhydrous (reported range -9.20 to -6.0) | water: anhydrous (0 wt%); MW (g/mol): 182.17","comments":"\"Sorbitol ... -9.20--6.0\" Table 3 polyol physicochemical properties; Tg reported as range -9.20 to -6.0 C. [reported: -9.20 to -6.0 C; confidence: high; Poka MS, Milne M, Wessels A, Aucamp M (2023)]"},{"id":84,"substance":"Sorbitol","glass_transition_temperature":"-4.1","doi":"10.1063/1.5037305","method":"Experiment","conditions":"DSC, onset Tg on heating at 10 K/min after cooling at 10...","conditions_detail":"DSC, onset Tg on heating at 10 K/min after cooling at 10 K/min (anhydrous D-sorbitol) | water: anhydrous (0 wt%); MW (g/mol): 182.17","comments":"\"D-sorbitol 269 353 26.7\" Table 1, Tg(K)=269. Tg is onset during heating at 10 K/min, following cooling at 10 K/min. Value attributed to Ref. 22. [reported: 269 K; confidence: high; Huang C, Chen Z, Gui Y, Shi C, Zhang GGZ, Yu L (2018)]"},{"id":85,"substance":"Xylitol","glass_transition_temperature":"-29","doi":"10.1111/j.1541-4337.2010.00136.x","method":"Experiment","conditions":"DSC anhydrous (Table 4, completely dried glass)","conditions_detail":"DSC anhydrous (Table 4, completely dried glass) | water: anhydrous (0 wt%); MW (g/mol): 152.15","comments":"\"Table 4-T g values for various sweeteners (assumes completely dried glass) ... Xylitol ... -29\" Table 4 row Xylitol, Tg = -29 C. [reported: -29 C; confidence: high; Hartel RW, Ergun R, Vogel S (2011)]"},{"id":86,"substance":"Xylitol","glass_transition_temperature":"-24.1","doi":"10.3390/pharmaceutics15112557","method":"Experiment","conditions":"DSC anhydrous","conditions_detail":"DSC anhydrous | water: anhydrous (0 wt%); MW (g/mol): 152.15","comments":"\"Xylitol ... -24.10\" Table 3 polyol physicochemical properties; Tg = -24.10 C. [reported: -24.1 C; confidence: high; Poka MS, Milne M, Wessels A, Aucamp M (2023)]"},{"id":87,"substance":"Xylitol","glass_transition_temperature":"-23.1","doi":"10.1063/1.5037305","method":"Experiment","conditions":"DSC, onset Tg on heating at 10 K/min after cooling at 10...","conditions_detail":"DSC, onset Tg on heating at 10 K/min after cooling at 10 K/min (anhydrous D-xylitol) | water: anhydrous (0 wt%); MW (g/mol): 152.15","comments":"\"D-xylitol 250 366 37.3 (0.7)\" Table 1, Tg(K)=250 ('This work'). Onset, 10 K/min. [reported: 250 K; confidence: high; Huang C, Chen Z, Gui Y, Shi C, Zhang GGZ, Yu L (2018)]"},{"id":88,"substance":"Mannitol","glass_transition_temperature":"10.7","doi":"10.1021/js970224o","method":"Experiment","conditions":"DSC, Tg onset (glass properties of D-mannitol via extrapo...","conditions_detail":"DSC, Tg onset (glass properties of D-mannitol via extrapolation using sorbitol as impurity) | water: anhydrous (0 wt%); MW (g/mol): 182.17","comments":"\"Tg onset = 10.7 C, Tg midpoint = 12.6 C, Tg end = 18.4 degC\" Mannitol Tg obtained by extrapolation to zero sorbitol because mannitol crystallizes too readily to measure directly. Onset 10.7, midpoint 12.6, end 18.4 C. [reported: 10.7 C; confidence: high; Yu L, Mishra DS, Rigsbee DR (1998)]"},{"id":89,"substance":"Mannitol","glass_transition_temperature":"10.7","doi":"10.3390/pharmaceutics15112557","method":"Experiment","conditions":"DSC anhydrous","conditions_detail":"DSC anhydrous | water: anhydrous (0 wt%); MW (g/mol): 182.17","comments":"\"Mannitol ... 10.7\" Table 3 polyol physicochemical properties; Tg = 10.7 C (consistent with Yu et al. 1998). [reported: 10.7 C; confidence: high; Poka MS, Milne M, Wessels A, Aucamp M (2023)]"},{"id":90,"substance":"Maltitol","glass_transition_temperature":"39","doi":"10.1111/j.1541-4337.2010.00136.x","method":"Experiment","conditions":"DSC anhydrous (Table 4, completely dried glass)","conditions_detail":"DSC anhydrous (Table 4, completely dried glass) | water: anhydrous (0 wt%); MW (g/mol): 344.31","comments":"\"Table 4-T g values for various sweeteners (assumes completely dried glass) ... Maltitol ... 39\" Table 4 row Maltitol, Tg = 39 C. Maltitol is a disaccharide polyol. [reported: 39 C; confidence: high; Hartel RW, Ergun R, Vogel S (2011)]"},{"id":91,"substance":"Maltitol","glass_transition_temperature":"43.1 to 49.5","doi":"10.3390/pharmaceutics15112557","method":"Experiment","conditions":"DSC anhydrous (reported range)","conditions_detail":"DSC anhydrous (reported range) | water: anhydrous (0 wt%); MW (g/mol): 344.31","comments":"\"Maltitol ... 43.1-49.5\" Table 3 polyol physicochemical properties; Tg range 43.1 to 49.5 C. [reported: 43.1 to 49.5 C; confidence: high; Poka MS, Milne M, Wessels A, Aucamp M (2023)]"},{"id":92,"substance":"Erythritol","glass_transition_temperature":"-45.0 to -42.50","doi":"10.3390/pharmaceutics15112557","method":"Experiment","conditions":"DSC anhydrous (reported range)","conditions_detail":"DSC anhydrous (reported range) | water: anhydrous (0 wt%); MW (g/mol): 122.12","comments":"\"Erythritol ... -45.0--42.50\" Table 3 polyol physicochemical properties; Tg range -45.0 to -42.50 C. Erythritol crystallizes rapidly so direct glass measurement is difficult. [reported: -45.0 to -42.50 C; confidence: high; Poka MS, Milne M, Wessels A, Aucamp M (2023)]"},{"id":93,"substance":"Glycerol","glass_transition_temperature":"-84.1","doi":"10.1063/1.5037305","method":"Experiment","conditions":"DSC, onset Tg on heating at 10 K/min after cooling at 10...","conditions_detail":"DSC, onset Tg on heating at 10 K/min after cooling at 10 K/min (anhydrous glycerol) | water: anhydrous (0 wt%); MW (g/mol): 92.09","comments":"\"Glycerol 189 291 18.3\" Table 1, Tg(K)=189. Attributed to Refs. 20,21. ~ -84 C. [reported: 189 K; confidence: high; Huang C, Chen Z, Gui Y, Shi C, Zhang GGZ, Yu L (2018)]"},{"id":94,"substance":"Glycerol","glass_transition_temperature":"-84","doi":"10.1039/D1CP02153B","method":"Experiment","conditions":"DSC onset Tg, pure glycerol (bulk sample)","conditions_detail":"DSC onset Tg, pure glycerol (bulk sample) | water: anhydrous (0 wt%); MW (g/mol): 92.09","comments":"\"189.1 +/- 1 K (bulk sample)\" Pure glycerol onset Tg from Table 2 (bulk). Value reported as 189.1 +/- 1 K. [reported: 189.1 K; confidence: medium; Angarita I, Mazzobre MF, Corti HR, Longinotti MP (2021)]"},{"id":95,"substance":"Arabitol","glass_transition_temperature":"-13.1","doi":"10.1063/1.5037305","method":"Experiment","conditions":"DSC, onset Tg on heating at 10 K/min after cooling at 10...","conditions_detail":"DSC, onset Tg on heating at 10 K/min after cooling at 10 K/min (anhydrous D-arabitol) | water: anhydrous (0 wt%); MW (g/mol): 152.15","comments":"\"D-arabitol 260 376 39.9 (0.2)\" Table 1, Tg(K)=260 ('This work'). Onset, 10 K/min. [reported: 260 K; confidence: high; Huang C, Chen Z, Gui Y, Shi C, Zhang GGZ, Yu L (2018)]"},{"id":96,"substance":"Dextran","glass_transition_temperature":"151.8","doi":"10.3390/pharmaceutics12060483","method":"Experiment","conditions":"DSC, MW 1.0 kDa; Tg vs molecular weight series (data from...","conditions_detail":"DSC, MW 1.0 kDa; Tg vs molecular weight series (data from Larsen et al. 2018) | MW (g/mol): 1000","comments":"\"1.0 kDa ... 151.8 +/- 0.2 (Tg, C)\" Table 1; Tg of dextran fraction; original source Larsen et al., Pharm Dev Technol 2018, doi:10.1080/10837450.2018.1479866. Hydration state not explicitly stated. [reported: 151.8 C; confidence: high; Asgreen C, Knopp MM, Skytte J, Lobmann K (2020)]"},{"id":97,"substance":"Dextran","glass_transition_temperature":"162.4","doi":"10.3390/pharmaceutics12060483","method":"Experiment","conditions":"DSC, MW 1.6 kDa; Tg vs molecular weight series","conditions_detail":"DSC, MW 1.6 kDa; Tg vs molecular weight series | MW (g/mol): 1600","comments":"\"1.6 kDa ... 162.4 +/- 1.1 (Tg, C)\" Table 1; original source Larsen et al. 2018. [reported: 162.4 C; confidence: high; Asgreen C, Knopp MM, Skytte J, Lobmann K (2020)]"},{"id":98,"substance":"Dextran","glass_transition_temperature":"194.8","doi":"10.3390/pharmaceutics12060483","method":"Experiment","conditions":"DSC, MW 3.7 kDa; Tg vs molecular weight series","conditions_detail":"DSC, MW 3.7 kDa; Tg vs molecular weight series | MW (g/mol): 3700","comments":"\"3.7 kDa ... 194.8 +/- 0.4 (Tg, C)\" Table 1; original source Larsen et al. 2018. [reported: 194.8 C; confidence: high; Asgreen C, Knopp MM, Skytte J, Lobmann K (2020)]"},{"id":99,"substance":"Dextran","glass_transition_temperature":"204.4","doi":"10.3390/pharmaceutics12060483","method":"Experiment","conditions":"DSC, MW 5.2 kDa; Tg vs molecular weight series","conditions_detail":"DSC, MW 5.2 kDa; Tg vs molecular weight series | MW (g/mol): 5200","comments":"\"5.2 kDa ... 204.4 +/- 0.8 (Tg, C)\" Table 1; original source Larsen et al. 2018. [reported: 204.4 C; confidence: high; Asgreen C, Knopp MM, Skytte J, Lobmann K (2020)]"},{"id":100,"substance":"Dextran","glass_transition_temperature":"212.8","doi":"10.3390/pharmaceutics12060483","method":"Experiment","conditions":"DSC, MW 9.6 kDa; Tg vs molecular weight series","conditions_detail":"DSC, MW 9.6 kDa; Tg vs molecular weight series | MW (g/mol): 9600","comments":"\"9.6 kDa ... 212.8 +/- 0.9 (Tg, C)\" Table 1; original source Larsen et al. 2018. [reported: 212.8 C; confidence: high; Asgreen C, Knopp MM, Skytte J, Lobmann K (2020)]"}]}